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This volume covers the most important parasitic protists that are known to infect humans. The pathogens discussed cause diseases like toxoplasmosis, malaria, cryptosporidiosis, leishmaniasis, amoebiasis, trichomoniasis, and giardiasis. Readers from microbiology will appreciate the special focus on protist cell biology. As demonstrated in several of the chapters, these parasites are characterized by peculiar structures and organelles that cannot be found in mammalian cells – even though both are eukaryotic. The book employs light and electron microscopy to display the changing morphology in various stages of parasitic development. In turn, the results are supplemented by transcriptome and proteome profiles that help to describe how these changes take place on a molecular level. Both researchers and clinicians from tropical medicine will find essential and practically applicable background information on these increasingly important pathogens.
This unique book provides an introduction to the fascinating field of tropical nephrology, covering nephrology, infectious diseases and tropical medicine. These topics are connected since numerous infectious and parasitic diseases affect the kidneys and are endemic in the tropical areas of the globe. Considered neglected tropical diseases by the World Health Organization, they are largely linked to poverty and lack policies to prevent, treat and decrease their prevalence and incidence. The tropics currently encompass nearly 150 countries and account for 40% of the world's population, and it is predicted that by 2050 this figure will rise to 55%. Most of the countries in the tropical regions ...
Public–private partnerships (PPPs) play an increasingly prominent role in addressing global development challenges. United Nations agencies and other organizations are relying on PPPs to improve global health, facilitate access to scientific information, and encourage the diffusion of climate change technologies. For this reason, the 2030 Agenda for Sustainable Development highlights their centrality in the implementation of the Sustainable Development Goals (SDGs). At the same time, the intellectual property dimensions and implications of these efforts remain under-examined. Through selective case studies, this illuminating work contributes to a better understanding of the relationships between PPPs and intellectual property considered within a global knowledge governance framework, that includes innovation, capacity-building, technological learning, and diffusion. Linking global governance of knowledge via intellectual property to the SDGs, this is the first book to chart the activities of PPPs at this important nexus.
Given its continent-like diversity, India’s epidemiological, nutritional, and demographic transitions are occurring in a staggered fashion, with high state-level variances. In many parts of the country, high rates of undernutrition co-exist with equally high and increasing rates of overweight and obesity. Further, the incidence of non-communicable diseases (NCDs) as a leading cause of mortality is increasing, even as the communicable, maternal, neonatal and nutritional causes (or the “Millennium Development Goals (MDG) conditions”) are coming down. Indeed, India has witnessed inconsistent progress towards the MDGs, and even in states where absolute levels of “MDG conditions” are still high, the NCD proportion is growing rapidly. The imperative is for a realignment of policy responding to fast-changing subnational realities, through greater integration between health and nutrition policy at every level of governance.
Kin Recognition in Protists and Other Microbes is the first volume dedicated entirely to the genetics, evolution and behavior of cells capable of discriminating and recognizing taxa (other species), clones (other cell lines) and kin (as per gradual genetic proximity). It covers the advent of microbial models in the field of kin recognition; the polymorphisms of green-beard genes in social amebas, yeast and soil bacteria; the potential that unicells have to learn phenotypic cues for recognition; the role of clonality and kinship in pathogenicity (dysentery, malaria, sleeping sickness and Chagas); the social and spatial structure of microbes and their biogeography; and the relevance of unicells’ cooperation, sociality and cheating for our understanding of the origins of multicellularity. Offering over 200 figures and diagrams, this work will appeal to a broad audience, including researchers in academia, postdoctoral fellows, graduate students and research undergraduates. Science writers and college educators will also find it informative and practical for teaching.
This ebook describes the pathogenesis of malaria and the major consequences of the parasitism to the vertebrate host. Malaria is one of the oldest infectious diseases of mankind, which still exerts a high burden on human health and society. It is caused by parasites of the genus Plasmodium, and transmitted by Anopheline mosquitoes. Despite several decades of intensive control efforts, malaria remains widely distributed with an estimated 3.3 billion of the world’s population at risk of infection. The malaria life cycle is extremely complex and the blood stage parasites are responsible for all the symptoms and pathology of malaria. Because of this strict association between the parasites and red cells, there are numerous consequences to the host’s blood extending far beyond the direct effect of parasitized RBCs.
Quinta raccolta dei post pubblicati nel "Blog di Luigi Cocola – Per un nuovo Risorgimento" Quarta Edizione
Em uma pandemia, qual é o papel da Bioética? O livro que ora se apresenta nasceu dessa pergunta, a partir da inquietação que eu tive ao ter alguns artigos sobre questões bioéticas na pandemia recusados em grandes revistas, sob a justificativa de que, nesse momento, o tipo de pesquisa que precisamos é "mais prático e mais efetivo". Nas origens da bioética estão as pesquisas com seres humanos realizadas durante a Segunda Guerra Mundial, a descoberta do DNA, do transplante de órgãos, das máquinas que substituem funções orgânicas, o famigerado caso Tuskegee e a discussão sobre alocação de uma máquina de hemodiálise para centenas de pacientes em um hospital em Seattle. Desde ...