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The Cambrian Fossils of Chengjiang, China
The Chengjiang biota is one of the most remarkable fossil discoveries ever made. The Cambrian Fossils of Chengjiang is the first book in English to provide fossil enthusiasts with an overview of the fauna. 100 superb full color plates. First English language illustrated guide to this important fauna. A must-have for all palaeontologists worldwide. To see a collection of images from the book, click on the following link: http://www.blackwellpublishing.com/chengjiang
The Cambrian Fossils of Chengjiang, China
The celebrated lower Cambrian Chengjiang biota of Yunnan Province, China, represents one of the most significant ever paleontological discoveries. Deposits of ancient mudstone, about 520 million years old, have yielded a spectacular variety of exquisitely preserved fossils that record the early diversification of animal life. Since the discovery of the first specimens in 1984, many thousands of fossils have been collected, exceptionally preserving not just the shells and carapaces of the animals, but also their soft tissues in fine detail. This special preservation has produced fossils of rare beauty; they are also of outstanding scientific importance as sources of evidence about the origins...
Sphingolipids and Metabolic Disease
Current thinking holds that obesity derives primarily from overnutrition (though compelling arguments for other mechanisms, like endocrine disruption by environmental pollutants, also gain support from the literature). In animals, overnutrition is initially handled by adipose tissue expansion; however, exhaustion of this route of lipid sequestering results in oversupply of lipid to other tissues including skeletal muscle, heart, liver, and others. Failure of these tissues to clear excess lipids through either metabolism or sequestration into putatively inert triacylglycerols results in perturbation of bioactive lipid metabolism in cells. In particular, aberrant generation of bioactive sphingolipids is implicated in a multitude of pathological outcomes of metabolic disease including insulin resistance, inflammation, cardiomyopathy, and others. This volume addresses not only the fundamentals of sphingolipid metabolism and analysis, but also the roles of sphingolipids in these disease processes.
The HDL Handbook
The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol. - Provides bench-to-bedside coverage of HDL with thorough coverage of basic science, genetics, epidemiology, and treatment - Presents a complete update with six new chapters on the latest advances in HDL cholesterol research with international perspective - New chapters on proteomics, clinical impact of LCAT in HDL metabolism, and an in-depth discussion of potential targets to modify HDL provide a translational reference for clinicians
Phospholipases in Physiology and Pathology
Phospholipases in Physiology and Pathology presents a comprehensive overview on the physiology and pathology of phospholipases. This seven-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Volumes cover signal transduction mechanisms, implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases, implications in inflammation, apoptosis, gene expression and non-coding RNAs, the role of natural and synthetic compounds, and stem cell therapies, nanotechnology-based therapies, and more. Together, these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases. - Discusses the biochemical and molecular mechanisms of normal and abnormal cell function in different disease processes - Covers a wide range of basic and translational research appropriate for scientists engaged in studying the regulation of phospholipases from interdisciplinary perspectives - Features state-of-the-art chapter contributions from international leaders in the field
Sphingolipids in Disease
Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative ceramide. The function of Sphingolipids in cell signaling with regard to infectious and lung diseases, cancer, cardiovascular diseases and neuropsychiatric disorders are described and treated in distinct parts. Together with Volume 215 from the same Editors, the collection represents a unique, comprehensive work on Sphingolipids, providing information on both: Sphingolipid basic biology as well as its important function in a (patho)physiological context. The book is written for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians in pharmacology, oncology, cardiology, neurology and infectious disease. ​
Records of Han Dynasty
Zi Zhi Tong Jian (Chinese: 资治通鉴;English: "Comprehensive Mirror in Aid of Governance") is a pioneering reference work in Chinese historiography, published in 1084 in the form of a chronicle. In 1065 AD, Emperor Yingzong of Songordered the great historian Sima Guang (1019–1086 AD) to lead with other scholars such as his chief assistants Liu Shu, Liu Ban and Fan Zuyu,[1] the compilation of a universal history of China. The task took 19 years to be completed,and, in 1084 AD, it was presented to his successor Emperor Shenzong of Song. The Zizhi Tongjian records Chinese history from 403 BC to 959 AD, covering 16 dynasties and spanning across almost 1,400 years,and contains 294 volumes (å...
