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Modern Alkaloids
This book presents all important aspects of modern alkaloid chemistry, making it the only work of its kind to offer up-to-date and comprehensive coverage. While the first part concentrates on the structure and biology of bioactive alkaloids, the second one analyzes new trends in alkaloid isolation and structure elucidation, as well as in alkaloid synthesis and biosynthesis. A must for biochemists, organic, natural products, and medicinal chemists, as well as pharmacologists, pharmaceutists, and those working in the pharmaceutical industry.
Herbal and Traditional Medicine
Responding to the increased popularity of herbal medicines and other forms of complementary or alternative medicine in countries around the world, this reference reviews and evaluates various safety, toxicity, and quality-control issues related to the use of traditional and herbal products for health maintenance and disease prevention and treatment. With over 3,550 current references, the book highlights the role of herbal medicine in national health care while providing case studies of widely used herbal remedies and their effects on human health and wellness and the need for the design and performance of methodologically sound clinical trials for the plethora of herbal medicines.
Temporal Coding in the Brain
Temporal coding in the brain documents a revolution now occurring in the neurosciences. How does parallel processing of information bind together the complex nature of the outer and our inner worlds? Do intrinsic oscillations and transient cooperative states of neurons represent the physiological basis of cognitive and motor functions of the brain? Some answers to these challenging issues are provided in this book by leading world experts of brain function. A common denominator of the works presented in this volume is the nature and mechanisms of neuronal cooperation in the temporal domain. The topics range from simple organisms to the human brain. The volume is intended for investigators and graduate students in neurophysiology, cognitive neuroscience, neural computation and neurology.
Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders
In this volume are contributions based on a meeting arranged by the WHO and the Fondation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer's Disease, Chromosome 17-Linked Dementia, Parkinson's Disease and disorders with tauopathies.
Knowledge Science, Engineering and Management
This three-volume set constitutes the refereed proceedings of the 14th International Conference on Knowledge Science, Engineering and Management, KSEM 2021, held in Tokyo, Japan, in August 2021. The 164 revised full papers were carefully reviewed and selected from 492 submissions. The contributions are organized in the following topical sections: knowledge science with learning and AI; knowledge engineering research and applications; knowledge management with optimization and security.
Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate
Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegenerative disorders? Brain development and function require complex cellular and molecular processes controlled by a number of different signaling mechanisms. One such signaling mechanism, the Notch pathway, has been recognized as an important player in the regulation of cellfate decisions during early neural development. However, the action of this evolutionary conserved and widely used cell-cell interaction mechanism is not confined to the developing nervous system. In addition, recent studies have shown that elucidating the mechanism of Notch signaling and its role in the brain is important for our understanding of neurological disorders such as Alzheimer's disease and cerebral arteriopathy CADASIL.
Understanding Animal Behaviour
Studying behaviour in animals requires numerical measurement. This book provides a scientific framework for what to measure and why.
Botanical Dietary Supplements:
This volume provides reviews and details of the quality, safety and efficacy for some of the top-selling botanicals worldwide, including black cohosh, chamomile, comfrey, echinacea, garlic, ginkgo, ginseng, kava, milk thistle, St John's wort and valerian. The work was written based on a systematic review of the scientific literature from 1975-2000.;Each review includes a brief introduction, a section on quality including a definition of the crude drug, geographical distribution, and a listing of the major chemical constituents. The safety and efficacy sections summarize the medical uses, pharmacology, contraindications, warnings, precautions, adverse reactions, dose and dosage forms. The safety and efficacy sections were written for a busy health-care professional, and should enable one to ascertain which clinical uses are supported by clinical data, without having to read through all the pharmacology. Each chapter is fully referenced, enabling the reader to access further information when necessary.
Challenges and Innovations in Geomechanics
This book gathers the latest advances, innovations, and applications in the field of computational geomechanics, as presented by international researchers and engineers at the 16th International Conference of the International Association for Computer Methods and Advances in Geomechanics (IACMAG 2020/21). Contributions include a wide range of topics in geomechanics such as: monitoring and remote sensing, multiphase modelling, reliability and risk analysis, surface structures, deep structures, dams and earth structures, coastal engineering, mining engineering, earthquake and dynamics, soil-atmosphere interaction, ice mechanics, landfills and waste disposal, gas and petroleum engineering, geothermal energy, offshore technology, energy geostructures, geomechanical numerical models and computational rail geotechnics.
