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The multivariate normal distribution has played a predominant role in the historical development of statistical theory, and has made its appearance in various areas of applications. Although many of the results concerning the multivariate normal distribution are classical, there are important new results which have been reported recently in the literature but cannot be found in most books on multivariate analysis. These results are often obtained by showing that the multivariate normal density function belongs to certain large families of density functions. Thus, useful properties of such families immedi ately hold for the multivariate normal distribution. This book attempts to provide a com...
This comprehensive resource covers the fundamentals of synthesis, characterizations, recent progress, and applications of nanowires for many emerging applications. Early chapters address their unique properties and morphology that enable their electronic, optical, and mechanical properties to be tuned. Later chapters address future perspectives and future challenges in areas where nanowires could provide possible solutions. All chapters are written by global experts, making this a suitable textbook for students and an up-to-date handbook for researchers and industry professionals working in physics, chemistry, materials, energy, biomedical, and nanotechnology. Covers materials, chemistry, and technologies for nanowires. Covers the state-of-the-art progress and challenges in nanowires. Provides fundamentals of the electrochemical behavior of various electrochemical devices and sensors. Offers insights on tuning the properties of nanowires for many emerging applications. Provides a new direction and understanding to scientists, researchers, and students.
Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pa...
This book aims to provide an overview of the design, limitations and challenges of heterogeneous catalysts for energy applications.
The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.
The growth in the use of mobile networks has come mainly with the third generation systems and voice traffic. With the current third generation and the arrival of the 4G, the number of mobile users in the world will exceed the number of landlines users. Audio and video streaming have had a significant increase, parallel to the requirements of bandwidth and quality of service demanded by those applications. Mobile networks require that the applications and protocols that have worked successfully in fixed networks can be used with the same level of quality in mobile scenarios. Until the third generation of mobile networks, the need to ensure reliable handovers was still an important issue. On the eve of a new generation of access networks (4G) and increased connectivity between networks of different characteristics commonly called hybrid (satellite, ad-hoc, sensors, wired, WIMAX, LAN, etc.), it is necessary to transfer mechanisms of mobility to future generations of networks. In order to achieve this, it is essential to carry out a comprehensive evaluation of the performance of current protocols and the diverse topologies to suit the new mobility conditions.
In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until recent methodological advances. This book evaluates newly generated empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context, provide evidence regarding the relative importance of gene duplication. The alternative explanation is that the evolution of regulatory elements that control the expression of and interactions among genes has been a more important force in shaping evolutionary innovation. This collection of papers will be of interest to all academic and industry researchers working in the fields of molecular biology, biotechnology, genomics and genome centers.