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This volume thoroughly describes the fundamentals of a new multidisciplinary field of study that aims to deepen our understanding of the human body by combining medical image processing, mathematical analysis, and artificial intelligence. Multidisciplinary Computational Anatomy (MCA) offers an advanced diagnosis and therapeutic navigation system to help detect or predict human health problems from the micro-level to macro-level using a four-dimensional, dynamic approach to human anatomy: space, time, function, and pathology. Applying this dynamic and “living” approach in the clinical setting will promote better planning for – and more accurate, effective, and safe implementation of – medical management. Multidisciplinary Computational Anatomy will appeal not only to clinicians but also to a wide readership in various scientific fields such as basic science, engineering, image processing, and biomedical engineering. All chapters were written by respected specialists and feature abundant color illustrations. Moreover, the findings presented here share new insights into unresolved issues in the diagnosis and treatment of disease, and into the healthy human body.
J. Brinckmann: Collagens at a Glance.- J. Engel, H.P. Bächinger: Structure, Stability and Folding of the Collagen Triple Helix.- S. Ricard-Blum, F. Ruggiero, M. van der Rest: The Collagen Superfamily.- T. Koide, K. Nagata: Collagen Biosynthesis.- J. Myllyharju: Intracellular Post-Translational Modifications of Collagens.- D.S. Greenspan: Biosynthetic Processing of Collagen Molecules.- D.E. Birk, P. Bruckner: Collagen Suprastructures.- D.R. Eyre, J.-J. Wu: Collagen Cross-Links
The articles in this volume cover the various options of the optimal management of brain tumors, vascular lesions, and functional disorders. They provide a good balance between microneurosurgery and radiosurgery, presenting also alternative surgical and radiosurgical treatment options with discussions on their advantages and disadvantages. The presentation of multiple treatment methods will help to provide better service to patients. Some papers, specifically highlighting alternative treatment options, are accompanied by editorials prepared by recognized experts in the field. Additional emphasis is put on importance of the advanced neuroimaging techniques for radiosurgical treatment planning and subsequent follow-up.
The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition o...
Intraoperative imaging technologies have taken an ever-increasing role in the daily practice of neurosurgeons and the increasing attention and interest necessitated international interaction and collaboration. The Intraoperative Imaging Society was formed in 2007. This book brings together highlights from the second meeting of the Intraoperative Imaging Society, which took place in Istanbul-Turkey from June 14 to 17, 2009. Included within the contents of the book is an overview of the emergence and development of the intraoperative imaging technology as well as a glimpse on where the technology is heading. This is followed by in detail coverage of intraoperative MRI technology and sections on intraoperative CT and ultrasonography. There are also sections on multimodality integration, intraoperative robotics and other intraoperative technologies. We believe that this book will provide an up-to date and comprehensive general overview of the current intraoperative imaging technology as well as detailed discussions on individual techniques and clinical results.
FROM THE REVIEWS OF THE PREVIOUS VOLUMES:"In perusing these chapters, I found much of interest. It is worth investigating."- P. Bricknell in BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY."Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."-BRITISH MEDICAL JOURNAL.* * Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology* Contributions from leaders in their fields* Abundant references
Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The appro...
Extracellular Matrix of the Liver addresses the basic science of the extracellular matrix and discusses new strategies for the treatment of cirrhosis of the liver, with a primary focus on possible gene therapy approaches. The chapters are divided into six sections as follows: * Basic Science of Extracellular Matrix * Cells Responsible for Extracellular Matrix Production * Activation Mechanism of Hepatic Cells and Signal Transduction * Basic Science for Extracellular Matrix Metabolism including Enzymes and their Inhibitors * Matrix Mettaloproteinases and Tissue Inhibitors for Matrix Mettaloproteinases * New Strategies for the treatment of Liver Cirrhosis Key Features * Discusses the possibility of gene therapy for liver cirrhosis * Includes information on new aspects of hepatic stellate cells * Written by top experts in basic science and clinical hepatology.
In the twenty-first century, applications in medicine and engineering must acquire greater safety and flexibility if they are to yield better products at higher efficiency. Experts from academia, industry, and government research laboratories who have pioneered CME ideas and technologies describe its concept and research approach and discuss related hardware and software, science and technology, and medicine and engineering. This book will be invaluable to scientists, researchers, and graduates in the emerging field of CME.
Applications of nuclear magnetic resonance span a wide range of scientific disciplines, from chemistry and physics to medicine. For those wanting to become acquainted with NMR or seasoned practitioners, this is a valuable source of current methods and applications.