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Cancer immunotherapy, including immune checkpoint inhibitors (ICIs) and chimeric antigen receptor T-cell (CAR-T) therapy, has revolutionized the paradigm in cancer treatment. However, the clinical outcome of immunotherapy varies considerably among patients and only a minority of patients achieve long-term clinical benefits. This is largely attributed to the fact that existing cancer immunotherapies, which concentrate on several classical targets (CTAL-4, PD-1/PD-L1, etc.) and limited types of immune cell populations (T cells), are insufficient to cope with the complexity of highly heterogeneous tumor microenvironment (TME). This calls for more efforts to not only expand our toolbox for manip...
The application of CMOS circuits and ASIC VLSI systems to problems in medicine and system biology has led to the emergence of Bio/CMOS Interfaces and Co-Design as an exciting and rapidly growing area of research. The mutual inter-relationships between VLSI-CMOS design and the biophysics of molecules interfacing with silicon and/or onto metals has led to the emergence of the interdisciplinary engineering approach to Bio/CMOS interfaces. This new approach, facilitated by 3D circuit design and nanotechnology, has resulted in new concepts and applications for VLSI systems in the bio-world. This book offers an invaluable reference to the state-of-the-art in Bio/CMOS interfaces. It describes leading-edge research in the field of CMOS design and VLSI development for applications requiring integration of biological molecules onto the chip. It provides multidisciplinary content ranging from biochemistry to CMOS design in order to address Bio/CMOS interface co-design in bio-sensing applications.
The aim of proceeding of International Conference on Material Engineering and Mechanical Engineering [MEME2015] is to provide a platform for researchers, engineers, and academicians, as well as industrial professionals, to present their research results and applications developed for Material Engineering and Mechanical Engineering. It provides an opportunities for the delegates to exchange new ideas and application experiences, to enhance business or research relations and to find global partners for future collaboration. The object is to strengthen national academic exchanges and cooperation in the field, promote the rapid development of machinery, materials science and engineering application, effectively improve China's machinery, materials science and engineering applications in the field of academic status and international influence.
The six volume set of LNCS 12622-12627 constitutes the proceedings of the 15th Asian Conference on Computer Vision, ACCV 2020, held in Kyoto, Japan, in November/ December 2020.* The total of 254 contributions was carefully reviewed and selected from 768 submissions during two rounds of reviewing and improvement. The papers focus on the following topics: Part I: 3D computer vision; segmentation and grouping Part II: low-level vision, image processing; motion and tracking Part III: recognition and detection; optimization, statistical methods, and learning; robot vision Part IV: deep learning for computer vision, generative models for computer vision Part V: face, pose, action, and gesture; video analysis and event recognition; biomedical image analysis Part VI: applications of computer vision; vision for X; datasets and performance analysis *The conference was held virtually.
Several plant bioactives or plant-derived therapeutic molecules have been used against life-threatening diseases and their nanoparticle-mediated delivery greatly improves therapeutic efficacy. Advances in Phytonanotechnology for Treatment of Various Diseases aims to describe past and recent advances achieved in the field of phytonanotechnology. The chapters of this book provide thorough knowledge of medicinal plants, plant bioactives, plant extract-based nanoparticle synthesis, delivery of plant bioactives through nanoparticles, and their therapeutic activity against life-threatening diseases. This book focuses on the therapeutic activity of phytocomponents present in plants from diverse fam...
This book constitutes the refereed proceedings of the Chinese Conference on Pattern Recognition, CCPR 2012, held in Beijing, China, in September 2012. The 82 revised full papers presented were carefully reviewed and selected from 137 submissions. The papers are organized in topical sections on pattern recognition theory; computer vision; biometric recognition; medical imaging; image and video analysis; document analysis; speech processing; natural language processing and information retrieval.
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