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Challenges and Current Research Status of Vertigo/Vestibular Diseases
  • Language: en
  • Pages: 346

Challenges and Current Research Status of Vertigo/Vestibular Diseases

Vertigo or vestibular disorders have become a common handicap across the globe, which poses a great burden on health care resources. Vertigo is not a disease entity per se, but rather a leading symptom of many etiologically different diseases. These conditions include dysfunction of the vestibular system, both peripheral (inner ear, vestibular nerve) and central (brainstem, cerebellum), functional dizziness, and diseases of other causes, including blood pressure regulation disorders, such as orthostatic dizziness, and adverse drug reactions. Previous studies demonstrated that vestibular disorders might be a modifiable condition and a possible target for secondary prevention of cognitive impairment due to aging, dementia, social isolation, late-life depression, frailty, and increased risk of mortality.

Design of Deep Braced Excavation in Urban Geotechnical Environments
  • Language: en
  • Pages: 484

Design of Deep Braced Excavation in Urban Geotechnical Environments

  • Type: Book
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  • Published: 2024-05-21
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  • Publisher: Elsevier

Design of Deep Braced Excavation in Urban Geotechnical Environments presents the design and calculation of deep braced excavation in urban geotechnical environments considering the soil characteristics of spatial variability and anisotropy, as well as excavation responses of urban adjacent utilities such as pipelines, tunnels, foundation piles and buildings. With economic development and further urbanization, excavation goes deeper, longer, and larger in scale. These conditions require advanced analysis and design methods. The text begins with coverage of overall stability, earth pressure and strut force, retaining wall responses, and ground movements. Numerical modeling and computer codes a...

Novel Molecular Targets and Treatments for Gastroesophageal Cancer, 2nd edition
  • Language: en
  • Pages: 236

Novel Molecular Targets and Treatments for Gastroesophageal Cancer, 2nd edition

Gastroesophageal cancer is among the most common malignant diseases worldwide and is associated with high mortality rates, leading to a substantial burden on public health and healthcare systems around the world. Chemotherapeutic drugs have achieved great success in the treatment of esophageal cancer; however, they also bring cytotoxicity to other organs and often have serious side effects. With the development of molecular diagnostics and biomarker discovery, the application of precision medicine has emerged to improve clinical outcomes. New antineoplastic therapy development is a timely topic in light of the recent development of precision medicine. New biotherapies aim to inhibit or regul...

Collaborative Computing: Networking, Applications and Worksharing
  • Language: en
  • Pages: 588

Collaborative Computing: Networking, Applications and Worksharing

This two-volume set constitutes the refereed proceedings of the 16th International Conference on Collaborative Computing: Networking, Applications, and Worksharing, CollaborateCom 2020, held in Shanghai, China, in October 2020. The 61 full papers and 16 short papers presented were carefully reviewed and selected from 211 submissions. The papers reflect the conference sessions as follows: Collaborative Applications for Network and E-Commerce; Optimization for Collaborate System; Cloud and Edge Computing; Artificial Intelligence; AI Application and Optimization; Classification and Recommendation; Internet of Things; Collaborative Robotics and Autonomous Systems; Smart Transportation.

Application of Soft Computing, Machine Learning, Deep Learning and Optimizations in Geoengineering and Geoscience
  • Language: en
  • Pages: 143

Application of Soft Computing, Machine Learning, Deep Learning and Optimizations in Geoengineering and Geoscience

This book summarizes the application of soft computing techniques, machine learning approaches, deep learning algorithms and optimization techniques in geoengineering including tunnelling, excavation, pipelines, etc. and geoscience including the geohazards, rock and soil properties, etc. The book features state-of-the-art studies on use of SC,ML,DL and optimizations in Geoengineering and Geoscience. Considering these points and understanding, this book will be compiled with highly focussed chapters that will discuss the application of SC,ML,DL and optimizations in Geoengineering and Geoscience. Target audience: (1) Students of UG, PG, and Research Scholars: Several applications of SC,ML,DL and optimizations in Geoengineering and Geoscience can help students to enhance their knowledge in this domain. (2) Industry Personnel and Practitioner: Practitioners from different fields can be able to implement standard and advanced SC,ML,DL and optimizations for solving critical problems of civil engineering.

Ubiquitin Code: From Cell Biology to Translational Medicine
  • Language: en
  • Pages: 249
New Insights Into Renal Fibrosis and Therapeutic Effects of Natural Products
  • Language: en
  • Pages: 353
Advances in Novel Drugs and Targets for Hepatic and Gastrointestinal Diseases
  • Language: en
  • Pages: 468

Advances in Novel Drugs and Targets for Hepatic and Gastrointestinal Diseases

The global incidence of gastrointestinal and hepatic diseases has been gradually increasing in recent years, which seriously threatens human health and increases the economic burden. More importantly, gastrointestinal and hepatic malignancies have the highest incidence and mortality rates among all tumors, such as liver cancer, stomach cancer, colon cancer, and pancreatic cancer. There are also non-neoplastic diseases such as viral hepatitis, cirrhosis, nonalcoholic steatohepatitis, chronic atrophic gastritis, ulcerative colitis, and reflux esophageal disease that also affect patients' quality of life. Although progress has been made in the pathogenesis of gastrointestinal and hepatic diseases, and corresponding therapeutic drugs have been also developed, the specific mechanisms of the diseases are still not revealed and there is a lack of specific drugs. In view of this, this topic aims to explore new molecular mechanisms of pathogenesis and potential therapeutic agents and pharmacological effects of gastrointestinal and hepatic diseases.

Seismic Geology and Basin Analysis
  • Language: en
  • Pages: 460

Seismic Geology and Basin Analysis

  • Type: Book
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  • Published: 2024-06-23
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  • Publisher: Elsevier

Seismic Geology and Basin Analysis: Case Studies on Sedimentary Basins in China introduces the principles, approaches and techniques needed to solve problems using seismic data calibrated with well log, cores and outcrop profiles. The book emphasizes the adoption of seismic techniques into basin analysis and broadens the usage of seismic data in geological research which may be referred to as “seismic geology. The principle of the book is mainly summarized from a series of case studies in different basins in China. In addition, through this book readers can understand the primary characteristics and basin fill evolution of major petroleum basins around the world. When starting research on ...

Cellular and Molecular Basis in Parasitic Diseases Control: Research Trends
  • Language: en
  • Pages: 536