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The Organizing Committee of the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases compiled a group of junior investigators to provide reviews on the topics they presented at the Puerto Vallarta Bioactive Lipids conference, as part of the book series, Advances in Experimental Medicine and Biology (AEMB). The book in this series will be titled Bioactive Lipids in Cancer, Inflammation and Related Diseases. Topics range from all classes of lipids including prostaglandins, resolvins, spingolipids, P450-derived lipids, endocannabanoids and phospholipids. The focus includes physiology, cell biology, and structural studies in organisms from bacteria to humans and how these studies addressed the role of lipids in various disease i.e. cancer, inflammation, diabetes, obesity, cardiovascular disease and others.
Creatures often suffer changes in conditions of their surroundings from the womb to the tomb through the climate alterations and their own movements, and may have various strategies in place to overcome such environmental changes. Among the conditions they encounter, the pH of environments surrounding creatures varies dramatically during lifespans, especially in microorganisms. In humans, the skin covering the body prevents acidification inside the body, and cells are surrounded by body fluid whose pH is kept at 7.4. Nevertheless, pH surrounding cells is often acidified, especially diseased areas, such as cancer nests, inflammatory loci, and infarction areas. Life sciences at the molecular l...
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