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Statistical Analysis of Human Growth and Development is an accessible and practical guide to a wide range of basic and advanced statistical methods that are useful for studying human growth and development. Designed for nonstatisticians and statisticians new to the analysis of growth and development data, the book collects methods scattered through
Stress is a physical response to an undesirable situation. Mild stress can result from missing the bus, standing in a long line at the store or getting a parking ticket. Stress can also be severe. Divorce, family problems, an assault, or the death of a loved one, for example, can be devastating. One of the most common sources of both mild and severe stress is work. Stress can be short-term (acute) or long-term (chronic). Acute stress is a reaction to an immediate threat -- either real or perceived. Chronic stress involves situations that aren't short-lived, such as relationship problems, workplace pressures, and financial or health worries. Stress is an unavoidable consequence of life. As Ha...
Fifty years ago, health outcomes in the countries of Eastern Europe and Central Asia were not far behind those in Western Europe and well ahead of most other regions of the world. But progress since then has been slow. While life expectancy in the ECA region today is close to the global average, the gap with its western neighbors has doubled, and other middle-income regions have all surpassed ECA. Some countries in the region are doing better, but full convergence with the world’s most advanced health systems is still a long way off. At the same time, survey evidence suggests that the health sector is the top priority for additional investment among populations across the region. The exper...
Designed for students training to become biostatisticians as well as practicing biostatisticians, Inference Principles for Biostatisticians presents the theoretical and conceptual foundations of biostatistics. It covers the theoretical underpinnings essential to understanding subsequent core methodologies in the field. Drawing on his extensive experience teaching graduate-level biostatistics courses and working in the pharmaceutical industry, the author explains the main principles of statistical inference with many examples and exercises. Extended examples illustrate key concepts in depth using a specific biostatistical context. In addition, the author uses simulation to reinforce the repeated sampling interpretation of numerous statistical concepts. Reducing the computational complexities, he provides simple R functions for conducting simulation studies. This text gives graduate students with diverse backgrounds across the health, medical, social, and mathematical sciences a solid, unified foundation in the principles of statistical inference. This groundwork will lead students to develop a thorough understanding of biostatistical methodology.
This book containes a series of "state of the art" essays on topics related to health and growth. The Commission on Growth and Development (CGD)--in preparing its own Growth Report--wished to take stock of the current state of knowledge and understanding of economic growth, and thus commissioned a series of essays on a range of thematic areas. One such area is health. The following questions are discussed in the book:Does investing in health raise economic growth? Can governments achieve rapid growth or high incomes without investing in health? What are the options and benefits of different an.
Early childhood is the most important stage of human development yet in Middle East and North Africa countries there is little research and inadequate investment in this crucial stage of life. This book covers risk, protective factors, policies and programs that can address inequality and shortfalls in the early years of life.
Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study. Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies. The book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas...
Many practitioners in the pharmaceutical industry are still largely unfamiliar with benefit-risk assessment, despite its growing prominence in drug development and commercialization. Helping to alleviate this knowledge gap, Benefit-Risk Assessment in Pharmaceutical Research and Development provides a succinct overview of the key considerations relevant to benefit-risk assessment across the pharmaceutical R&D spectrum, from early clinical development to late-stage development to regulatory review to post-launch assessment. The book first presents interpretations of benefit and risk in the context of a molecule moving from preclinical evaluation into its early testing in humans. It next consid...
This book examines how and why, in the context of International Relations, children’s subjecthood has all too often been relegated to marginal terrains and children themselves automatically associated with the need for protection in vulnerable situations: as child soldiers, refugees, and conflated with women, all typically with the accent on the Global South. Challenging us to think critically about childhood as a technology of global governance, the authors explore alternative ways of finding children and their agency in a more central position in IR, in terms of various forms of children’s activism, children and climate change, children and security, children and resilience, and in their inevitable role in governing the future. Focusing on the problems, pitfalls, promises, and prospects of addressing children and childhoods in International Relations, this book places children more squarely in the purview of political subjecthood and hence more centrally in IR.
Substantial progress in the fight against extreme poverty was made in the last two decades. But the slowdown in global economic growth and significant increases in income inequality in many developed and developing countries raise serious concerns about the continuation of this trend into the 21st century. The time has come to seriously think about how improvements in official global governance, coupled with and reinforced by rising activism of 'global citizens' can lead to welfare-enhancing and more equitable results for global citizens through better national and international policies. This book examines the factors that are most likely to facilitate the process of beneficial economic gro...