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This volume is a unique combination of papers that cover critical topics in biostatistics from academic, government, and industry perspectives. The 6 sections cover Bayesian methods in biomedical research; Diagnostic medicine and classification; Innovative Clinical Trials Design; Modelling and Data Analysis; Personalized Medicine; and Statistical Genomics. The real world applications are in clinical trials, diagnostic medicine and genetics. The peer-reviewed contributions were solicited and selected from some 400 presentations at the annual meeting of the International Chinese Statistical Association (ICSA), held with the International Society for Biopharmaceutical Statistics (ISBS). The conference was held in Bethesda in June 2013, and the material has been subsequently edited and expanded to cover the most recent developments.
"Examination of the social and demographic effects of the Ming-Qing transition on southwest China and the devastation wrought by the warlord Zhang Xianzhong"--Provided by publisher.
Until recently, central Indiana has not truly reflected the sheer diversity of races, religions, cultures, and ethnic backgrounds of the rest of the world. In recent decades and especially in the first years of the 21st century, however, cities, towns, and rural areas of the central portion of the Hoosier state have welcomed an increasing number of new residents who constitute a surprisingly broad and diverse cross section of world citizens. To capture and celebrate these changes, New Faces at the Crossroadsfeatures portraits of 30 recent newcomers from around the world by award-winning photographer Jeffrey A. Wolin, accompanied by stories of why they came to the area and their perspectives on living there. Together with John Sherman's text describing changes and additions to the region's population, these striking photographs show that central Indiana is no longer just the Crossroads of America: It is the crossroads of the world.
The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solve problems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems. It begins by introducing all the necessary probabilistic and statistical foundations, before moving on to topics related human genetic epidemiology, with R codes illustrations for various examples. This clear and concise book covers human genetic epidemiology, using R in data analysis, including multivariate data analysis. It examines probabilistic and statistical theories for...
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This contributed volume offers a much-needed overview of the statistical methods in early clinical drug and biomarker development. Chapters are written by expert statisticians with extensive experience in the pharmaceutical industry and regulatory agencies. Because of this, the data presented is often accompanied by real world case studies, which will help make examples more tangible for readers. The many applications of statistics in drug development are covered in detail, making this volume a must-have reference. Biomarker development and early clinical development are the two critical areas on which the book focuses. By having the two sections of the book dedicated to each of these topics...
Western historians have long speculated about Chinese military intervention in the Vietnam War. It was not until recently, however, that newly available international archival materials, as well as documents from China, have indicated the true extent and level of Chinese participation in the conflict of Vietnam. For the first time in the English language, this book offers an overview of the operations and combat experience of more than 430,000 Chinese troops in Indochina from 1968-73. The Chinese Communist story from the "other side of the hill" explores one of the missing pieces to the historiography of the Vietnam War. The book covers the chronological development and Chinese decision-maki...
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China will eine "Führungsnation" im Völkerrecht werden. Dieses Buch zeigt mit einer ersten umfassenden Analyse von Fallrecht und chinesischen akademischen Debatten von 2002 bis 2018, dass die verstärkte Nutzung von internationalen Gerichten Teil eines breiten Unterfangens ist, Chinas wirtschaftliche und politische Erfolge zu konsolidieren, und erneut Großmachtstatus zu erlangen. Handels- und Investmentrecht, Seerecht und territoriale Fragen werden abgedeckt – auch zum Südchinesischen Meer – und ein jahrzehntelanger Prozess zwischen Vorsicht und Ambition nachgezeichnet. Diskussionsmuster und tatsächliches Engagement Chinas in allen Rechtsbereichen zeigen bemerkenswerte Gemeinsamkeiten, lediglich die Zeitpläne sind unterschiedlich.