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Combinational Immunotherapy of Cancer: Novel Targets, Mechanisms, and Strategies
Cancer immunotherapy, including immune checkpoint inhibitors (ICIs) and chimeric antigen receptor T-cell (CAR-T) therapy, has revolutionized the paradigm in cancer treatment. However, the clinical outcome of immunotherapy varies considerably among patients and only a minority of patients achieve long-term clinical benefits. This is largely attributed to the fact that existing cancer immunotherapies, which concentrate on several classical targets (CTAL-4, PD-1/PD-L1, etc.) and limited types of immune cell populations (T cells), are insufficient to cope with the complexity of highly heterogeneous tumor microenvironment (TME). This calls for more efforts to not only expand our toolbox for manip...
Typhoon Impact and Crisis Management
Major natural hazards have sparked growing public concern worldwide. This book provides new information on Typhoon Impact and Crisis Management using satellite remote sensing technology, linking the natural sciences and social sciences in typhoon studies. It examines remote sensing observations of typhoons (hurricanes), typhoon impacts on the environment, typhoon impacts on marine ecosystems, typhoon impacts and global changes, typhoon (hurricane) impacts on economics, and crisis management for typhoon (hurricane) disasters.
China in the Era of Xi Jinping
In this collection, scholars examine the prospects for China's rise and the emergent and unintended consequences posed by China's internal challenges and international assertiveness. The result is a comprehensive analysis of current policy trends in Xi's China and the implications of these developments for his nation, the US, and East Asia.
Proceedings of the 2nd International Conference on Intelligent Design and Innovative Technology (ICIDIT 2023)
This is an open access book.The 2nd International Conference on Intelligent Design and Innovative Technology (ICIDIT 2023) will be held in Chengdu, China from August 04 to 06, 2023. This conference mainly focuses on the latest research on "Intelligent Design and Innovative Technology". This conference brings together experts, scholars, researchers and relevant practitioners in this field from all over the world to share research results, discuss hot issues, and provide participants with cutting-edge scientific and technological information, so that you can timely understand the development trends of the industry and master the latest technologies, broaden research horizons and promote academic progress.
Cellular and Molecular Toxicology of Nanoparticles
This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types. Readers will be benefited with the compilations...
GB/T 33598-2017 Translated English of Chinese Standard (GBT 33598-2017, GB/T33598-2017, GBT33598-2017)
This Standard specifies the terms and definitions, general requirements, operating procedures, storage and management requirements for vehicle used waste battery packs (cases), and module dismantling work. This Standard is applicable to the vehicle used waste lithium-ion traction battery, metal hydride nickel traction battery pack (case), and module dismantling; it is not applicable to the vehicle used waste traction battery single-cell dismantling.
