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This book presents an overview of the recent technologies in single molecule and single cell sequencing. These sequencing technologies are revolutionizing the way of the genomic studies and the understanding of complex biological systems. The PacBio sequencer has enabled extremely long-read sequencing and the MinION sequencer has made the sequencing possible in developing countries. New developments and technologies are constantly emerging, which will further expand sequencing applications. In parallel, single cell sequencing technologies are rapidly becoming a popular platform. This volume presents not only an updated overview of these technologies, but also of the related developments in bioinformatics. Without powerful bioinformatics software, where rapid progress is taking place, these new technologies will not realize their full potential. All the contributors to this volume have been involved in the development of these technologies and software and have also made significant progress on their applications. This book is intended to be of interest to a wide audience ranging from genome researchers to basic molecular biologists and clinicians.
A collection of papers dealing with complete systems of intelligent robots, focusing on autonomy. The contributions cover intelligent perception, intelligent planning and control, and integrated systems.
Joe Engelberger, the pioneer of the robotics industry, wrote in his 1989 book Robotics in Service that the inspiration to write his book came as a reaction to an industry-sponsored forecast study of robot applications, which predicted that in 1995 applications of robotics outside factories - the traditional domain of industrial robots - would amount to less than 1% of total sales. Engelberger believed that this forecast was very wrong, and instead predicted that the non-industrial class of robot applications would become the largest class. Engelbergers prediction has yet to come to pass. However, he did correctly foresee the growth in non-traditional applications of robots. Robots are now be...
Human Activity and Behavior Analysis relates to the field of vision and sensor-based human action or activity and behavior analysis and recognition. The book includes a series of methodologies, surveys, relevant datasets, challenging applications, ideas, and future prospects. The book discusses topics such as action recognition, action understanding, gait analysis, gesture recognition, behavior analysis, emotion and affective computing, and related areas. This volume focuses on relevant activities in three main subject areas: Healthcare and Emotion, Mental Health, and Nurse Care Records. The editors are experts in these arenas and the contributing authors are drawn from high-impact research groups around the world. This book will be of great interest to academics, students, and professionals working and researching in the field of human activity and behavior analysis.
PacBio’s single-molecule real-time (SMRT) sequencing technology offers important advantages over the short-read DNA sequencing technologies that currently dominate the market. This includes exceptionally long read lengths (20 kb or more), unparalleled consensus accuracy, and the ability to sequence native, non-amplified DNA molecules. From fungi to insects to humans, long reads are now used to create highly accurate reference genomes by de novo assembly of genomic DNA and to obtain a comprehensive view of transcriptomes through the sequencing of full-length cDNAs. Besides reducing biases, sequencing native DNA also permits the direct measurement of DNA base modifications. Therefore, SMRT sequencing has become an attractive technology in many fields, such as agriculture, basic science, and medical research. The boundaries of SMRT sequencing are continuously being pushed by developments in bioinformatics and sample preparation. This book contains a collection of articles showcasing the latest developments and the breadth of applications enabled by SMRT sequencing technology.
Offering voices from the field – the first of its kind outside of Japan – this guide to teaching and learning elementary mathematics highlights real case examples from teachers and educators who share what they have learned through Lesson Study. The teachers’ reports provide vivid examples of new insights and ideas about mathematics, about pedagogy and lesson design, about student learning, and about professional collaboration gained through Lesson Study. Each report includes an abbreviated plan of the specific research lesson that led to the new insights, which readers can draw from to replicate the powerful learning in their own community. The case examples of this book are from Less...
Offering a rich, critical investigation of how technology can be used to strengthen and promote lesson study in both virtual and hybrid environments, this edited book presents insights into the numerous challenges as well as opportunities for supporting teachers’ and teacher educators’ professional learning in such a novel setting. Providing an international perspective, research in this book highlights on the one hand the necessity of exploring how the known theoretical perspectives and methodological approaches for researching on lesson study and effective characteristics of conducting lesson study can be adapted to the new environments. On the other hand, further analysis reveals the ...
Health is defined as “the state of the organism when it functions optimally without evidence of disease”. Surprisingly, the words “microbes” or “microorganism” are missing in this definition. The regulation of gut microbiota is mediated by an enormous quantity of aspects, such as microbiological factors, host characteristics, diet patterns, and environmental variables. Some protective, structural, and metabolic functions have been reported for gut microbiota, and these functions are related to the regulation of homeostasis and host health. Host defense against pathogens is, in part, mediated through gut microbiota action and requires intimate interpretation of the current microen...
Data Science for Effective Healthcare Systems has a prime focus on the importance of data science in the healthcare domain. Various applications of data science in the health care domain have been studied to find possible solutions. In this period of COVID-19 pandemic data science and allied areas plays a vital role to deal with various aspect of health care. Image processing, detection & prevention from COVID-19 virus, drug discovery, early prediction, and prevention of diseases are some thrust areas where data science has proven to be indispensable. Key Features: The book offers comprehensive coverage of the most essential topics, including: Big Data Analytics, Applications & Challenges in...