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The Role of Omics Characteristics in the Diagnosis, Treatment, and Prognosis of Autoimmune Diseases
MW, YL and ZC were employed by Inner Mongolia Shuangqi Pharmaceutical Co.Ltd. XZ, FL, LC and ZC were employed by Shenzhen Wedge Microbiology Research Co.Ltd.
The Gut-Skin Axis: Interaction of Gut Microbiome and Skin Diseases
More and more evidence has demonstrated that gut microbiome plays critical roles in modulating the development of diseases beyond the gastrointestinal tract, including skin disorders such as psoriasis. The new conception ‘gut-skin axis’ refers to the bidirectional relationship between the gut microbiome and skin health. Several mechanisms, such as intestinal barrier, inflammatory mediators, and metabolites, have been proposed for gut-skin axis. Currently, there have been various studies regarding the presence of the gut-skin axis and its resulting inflammatory effect due to gut microbiome imbalance. In addition, dysbiosis of the skin and gut microbiota is also observed in skin disorders. Therefore, understanding the gut-skin axis, especially in terms of microbiome modulation, is important for the gut and skin health, which may lead to development of novel therapies for skin disease.
Flush
For readers of Giulia Enders’ Gut and Bill Bryson’s The Body, a surprising, witty and sparkling exploration of the teeming microbiome of possibility in human feces from microbiologist and science journalist Bryn Nelson. The future is sh*t: the literal kind. For most of human history we’ve been, well, disinclined to take a closer look at our body’s natural product—the complex antihero of this story—save for gleaning some prophecy of our own health. But if we were to take more than a passing look at our poop, we would spy a veritable cornucopia of possibilities. We would see potent medicine, sustainable power, and natural fertilizer to restore the world’s depleted lands. We would...
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