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Personalized or precision medicine (PM) is developing and adopting of the safest and most cost-effective therapeutic approach for each patient. PM approach aims to identify phenotypic and genotypic individual characteristics, observe how these parameters are correlated with the disease status, severity, and intervention responsiveness to predict the best personalized clinical protocol. On the other hand, the risk of severe toxicity and adverse effects might be related to the patient-specific characteristics.
This book provides a complete overview of two-dimension and three-dimension images of structures in normal and man-made minimal lesions in temporal bone. First chapters present a series of two-dimension reconstructions of the temporal bone made via micro-CT scanning on axial, coronal and sagittal view just as HRCT showed. Subsequent chapters address three-dimension reconstruction of the temporal bone, and some models of man-made lesions in the temporal bone were reconstructed via micro-CT scanning. Last chapter discusses differences between micro-CT and high resolution CT scan of temporal bone. This atlas is a valuable reference for otolaryngology & head and neck surgeons, radiologists, and related researchers.
An increasing number of studies suggest that the abnormality of substance and energy metabolism of tumor cells is among the unsolved complex pathological mechanism problems in malignant tumor. The abnormal metabolism of substance and energy in tumor cells is not only the cause of occurrence and development of malignant tumors, but also the concrete embodiment of their pathological changes. Substance and energy metabolism of tumor cells largely depends on neuroendocrine regulation, so it is of great scientific and clinical significance to analyze its regulatory mechanism. The imbalance of material and energy metabolism of tumor cells is one of the major causes for the occurrence and developme...
This book primarily summarizes the imaging characteristics and theory of parasitic disease, offering a clinical guide and practical approach to understanding, preventing and diagnosing parasitic disease. Through imaging diagnosis and cross-research of imaging with autopsy and pathology, it highlights the chief characteristics and evolution of imaging, which provides primary scientific data for the understanding and research of parasitic disease. Divided into 9 chapters, this volume is fully illustrated with DR, CT and MRI images of different kinds of parasitic diseases, providing a valuable resource for radiologists in this field.
Precision medicine is the main emphasis in healthcare after recognizing the importance to integrate the clinical data with the molecular data of a specific disease. The term was first introduced in 2015 in which the Precision Medicine Initiative was initiated with the final aim to provide targeted therapy with high efficacy and less toxicity. Precision medicine plays an increasingly important in gastrointestinal cancers. Gastrointestinal cancers are divided into the upper (esophagus, stomach) and lower part (hepatobiliary and colon) of the gastrointestinal system. We would like to explore the latest era of integrative therapeutic target in gastrointestinal cancers taking into consideration of various aetiologies including genetic and exposome (dietary factors, microbial, hormonal, environmental insults) and their interactions with the host microenvironment.
Zhenwu, or the Perfected Warrior, is one of the few Chinese Deities that can rightfully claim a countrywide devotion. Religious specialists, lay devotees, the state machine, and the cultural industry all participated, both collaboratively and competitively, in the evolution of this devotional movement. This book centres on the development and transformation of the godhead of Zhenwu, as well as the devotional movement focused on him. Organised chronologically on the development of the Zhenwu worship in Daoist rituals, state religion, and popular practices, it looks at the changes in the way Zhenwu was perceived, and the historical context in which those changes took place. The author investig...