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Immune Responses Against Tumors - From the Bench to the Bedside
Traditionally, surgery, radiotherapy, chemotherapy and hormonal therapy have been used in clinical practice to treat cancer patients. However, these methods are either not completely tumor free or without collateral damage to health tissues. Therefore, tumor recurrence, partial remission, treatment side effect and poor tolerance in elderly patients, and lack of effective strategy to treat late-stage cancers have been the major hurdles faced by clinicians in health care. Although cancer immunotherapy including checkpoint blockade, CAR-T, oncolytic viruses, and recombinant cytokines has taken center stage in mainstream oncology because of its specifically targeting tumor cells without affecting surrounding normal cells, only a proportion of patients receiving treatment respond and others relapse after an initial response. Different tumor indications respond differently, and even in cancer types that respond, unresponsiveness are still observed. This resistance suggests that either lack of sufficient host recognition and immunity (intrinsic) or active immune suppression by tumor complex (acquired).
Smart Micro- and Nanomaterials for Drug Delivery
Smart drug delivery at both the micro- and nanoscale is an evolving field with numerous potential applications. It has the potential to revolutionize drug therapy by making treatments more effective, reducing side effects, and improving patient outcomes. This book presents a comprehensive review of the most recent studies on smart micro- and nanomaterials with a focus on their “smart” activity for formation of targeted and responsive drug-delivery carriers. This volume: Introduces readers to the fundamentals of these the micro- and nanoscale materials as well as approaches to smart drug delivery and drug delivery systems. Covers polymers, metals, and composite materials as well as quantu...
Proceedings of the 2023 9th International Conference on Humanities and Social Science Research (ICHSSR 2023)
This is an open access book. 2023 9th International Conference on Humanities and Social Science Research (ICHSSR 2023) will be held on April 21-23, 2022 in Beijing, China. Except that, ICHSSR 2023 is to bring together innovative academics and industrial experts in the field of Humanities and Social Science Research to a common forum. We will discuss and study about EDUCATION , SOCIAL SCIENCES AND HUMANITIES, INTERDISCIPLINARY STUDIES and other fields. ICHSSR 2022 also aims to provide a platform for experts, scholars, engineers, technicians and technical R & D personnel to share scientific research achievements and cutting-edge technologies, understand academic development trends, expand research ideas, strengthen academic research and discussion, and promote the industrialization cooperation of academic achievements. The conference sincerely invites experts, scholars, business people and other relevant personnel from universities, scientific research institutions at home and abroad to attend and exchange! The conference will be held every year to make it an ideal platform for people to share views and experiences in financial innovation and economic development and related areas.
Rock Stress and Earthquakes
The evaluation of in-situ rock stress is not only important in the exploration and engineering involving rock masses for mining, hydropower, tunneling, oil and gas production, and stone quarrying, but also in the geodynamics and earthquake prediction. The methods of determining these stresses for shallow crust in the engineering practice, including
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Annual Report
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