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Novel Targets for Chronic Inflammatory Diseases: Focus On Therapeutic Drugs and Natural Compounds
Chronic inflammation is a component of many disease conditions that affect a large group of individuals worldwide, which is characterized by persistent, low-grade inflammation and is increased in the aging population. It occurs when an initiating stimulus is not removed or if the resolution process is disrupted, resulting in a state of low-grade inflammation. It is acknowledged that chronic inflammatory diseases are involved in cardiovascular diseases, endocrine disease, neurodegenerative disease, hepatic disease, pulmonary disease, gastrointestinal disease, and cancer et al., including but not limited to atherosclerosis, diabetes, multiple sclerosis, fibrosis, NAFLD, COPD, inflammatory bowel disease, autoimmune disorders (like SLE, RA), which are major causes of death worldwide. Therefore, it is necessary to explore novel targets and therapeutic drugs for chronic inflammatory diseases.
Integrative Pharmacology-based Research on Traditional Medicine: Methodologies, Medical and Pharmacological Applications
ntegrative Pharmacology can be used to determine the multi-pharmacological effects of traditional medicines such as traditional Chinese medicine (TCM), Kampo, Sa-sang, Ayurveda, etc.). Through qualitative and quantitative pharmacokinetic-pharmacodynamic (PK-PD) correlations among multi-constituents and multi-targets, integrating chemical profiling, ADME/PK processes, molecular network calculation and resulting experimental validation, the use of Integrative Pharmacology has become widespread. The data has provided a novel paradigm to evaluate the druggability of bioactive ingredients of herbs or formulae, to decipher the pharmacological mechanisms of drug action and to screen potentially new indications for approved drugs and previously unidentified adverse events. On this basis, Integrative Pharmacology may offer an effective way to test the potential scientific basis for traditional medicines and to assess what roles of traditional medicine can and cannot play in pharmaceuticals.
PRICAI 2000 Topics in Artificial Intelligence
PRICAI 2000, held in Melbourne, Australia, is the sixth Pacific Rim Interna tional Conference on Artificial Intelligence and is the successor to the five earlier PRICAIs held in Nagoya (Japan), Seoul (Korea), Beijing (China), Cairns (Aus tralia) and Singapore in the years 1990, 1992, 1994, 1996 and 1998 respectively. PRICAI is the leading conference in the Pacific Rim region for the presenta tion of research in Artificial Intelligence, including its applications to problems of social and economic importance. The objectives of PRICAI are: To provide a forum for the introduction and discussion of new research results, concepts and technologies; To provide practising engineers with exposure to ...
PRICAI 2021: Trends in Artificial Intelligence
This three-volume set, LNAI 13031, LNAI 13032, and LNAI 13033 constitutes the thoroughly refereed proceedings of the 18th Pacific Rim Conference on Artificial Intelligence, PRICAI 2021, held in Hanoi, Vietnam, in November 2021.The 93 full papers and 28 short papers presented in these volumes were carefully reviewed and selected from 382 submissions. PRICAI covers a wide range of topics in the areas of social and economic importance for countries in the Pacific Rim: artificial intelligence, machine learning, natural language processing, knowledge representation and reasoning, planning and scheduling, computer vision, distributed artificial intelligence, search methodologies, etc. Part II includes two thematic blocks: Natural Language Processing, followed by Neural Networks and Deep Learning.
AI 2001: Advances in Artificial Intelligence
This book constitutes the refereed proceedings of the 14th Australian Joint Conference on Artificial Intelligence, AI 2001, held in Adelaide, Australia, in December 2001. The 55 revised full papers presented together with one invited contribution were carefully reviewed and selected from a total of 100 submissions. The papers cover the whole range of artificial intelligence from theoretical and foundational issues to advanced applications in a variety of fields.
Advances in Image and Graphics Technologies
This book constitutes the refereed proceedings of the 12th Chinese Conference on Image and Graphics Technologies and Applications, IGTA 2017, held in Beijing, China June 30 – July 1, 2017. The 26 papers presented were carefully reviewed and selected from 78 submissions. They provide a forum for sharing progresses in the areas of image processing technology; image analysis and understanding; computer vision and pattern recognition; big data mining, computer graphics and VR; as well as image technology applications
AI 2001: Advances in Artificial Intelligence
This book constitutes the refereed proceedings of the 14th Australian Joint Conference on Artificial Intelligence, AI 2001, held in Adelaide, Australia, in December 2001. The 55 revised full papers presented together with one invited contribution were carefully reviewed and selected from a total of 100 submissions. The papers cover the whole range of artificial intelligence from theoretical and foundational issues to advanced applications in a variety of fields.
Knowledge Science, Engineering and Management
This two-volume set of LNAI 12274 and LNAI 12275 constitutes the refereed proceedings of the 13th International Conference on Knowledge Science, Engineering and Management, KSEM 2020, held in Hangzhou, China, in August 2020.* The 58 revised full papers and 27 short papers were carefully reviewed and selected from 291 submissions. The papers of the first volume are organized in the following topical sections: knowledge graph; knowledge representation; knowledge management for education; knowledge-based systems; and data processing and mining. The papers of the second volume are organized in the following topical sections: machine learning; recommendation algorithms and systems; social knowledge analysis and management; text mining and document analysis; and deep learning. *The conference was held virtually due to the COVID-19 pandemic.
