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This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Diso...
This is a comprehensive book addressing steroid disorders from hormonal, genetic, psychological, and surgical perspectives. It is meant to educate adult and pediatric endocrinologists, clinical geneticists, genetic counselors, reproductive endocrinologists, neonatologists, urologists, and psychoendocrinologists. It will assist these specialists in the diagnosis and treatment of steroid disorders. The book is written for postgraduate and faculty-level physicians. The content consists of steroid disorders, genetic bases for the disorder and case presentations of each disorder. Provides a common language for professionals to discuss and diagnose genetic steroid disorders Includes the very latest details on genetic tests and diagnoses Offers a strong understanding of the molecular basis for the diseases and therefore correct diagnosis and treatment of steroid disorders Presents insight into which medications to use based on the genetic makeup of a patient Teaches the best strategies and most effective use of genetic information in the patient counseling setting
The 2nd Edition of this essential text covers all aspects of female urology. Includes chapters on the anatomy of continence and pelvic support, retrocele repair, enterocele repair, hysterectomy, perineal repair, vaginal vault prolapse, sacrospinalis fixation, and continent pouches. Other material focuses on the treatment of urinary incontinence using functional electrical stimulation, needle urethral-vesicle suspension procedures, retropubic operative procedures for stress urinary incontinence, surgical treatment of detrusor hyperreflexia, gynecologic injuries to the ureter, bladder, and urethra, and vaginal flap technique.
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No detailed description available for "Molecular Nephrology".
Fashion Todayis a kaleidoscopic, colorful and provocative survey of the fashion world - from the introduction of Dior's New Look in 1947 to the present day. The book is a thematic overview of fashion in its widest sense imaginable: ranging from haute couture to street-style, from the one-off to the mass market, to the pret-a-porter. It illustrates, with elegance and flair, just how vital and everlasting a part fashion has played in reflecting and influencing twentieth-century attitudes: from the sexual revolution and rise of popular culture in the 1960s to the consumerism of the 1980s and 1990s. Fashion Todayplaces current fashion not only in the contexts of youth, sexuality, fetishism, exoticism and historicism, but also in the contexts of previous fashion movements: it demonstrates dynamically that fashion reflects not only its surroundings and its subjects but ultimately itself. Aesthetically and intellectually stimulating, this volume is a must-have for anyone who has even the vaguest interest in any aspect of the fashion world today. Its breadth of scope and depth of insight are unprecedented.
"Täyteläinen, rikas, moniääninen ja vetävä romaani." Helsingin Sanomat Kauneudesta on humoristisen älykäs aikalaisromaani etnisiltä taustoiltaan eroavien perheiden vaiheista ja valinnoista. Howard Belsey ja hänen arkkivihollisensa Monty Kipps ovat jo vuosia nokitelleet toisiaan samoissa akateemisissa ympyröissä. Jerome, Balseyn ateistiperheen musta lammas, ehtii jo säikäyttää isänsä suunnittelemalla häitä uskonnollisten Kippsien tyttären kanssa, mutta kaikkien onneksi seurustelu paljastuu vain "romanttiseksi sekoiluksi". Yhdeksän kuukautta myöhemmin Kippsit muuttavat Lontoosta Atlantin taakse Wellingtoniin, ja suorapuheiset perheenäidit intoutuvat tuota pikaa aviollis...
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