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Greene's Protective Groups in Organic Synthesis
The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence. This new edition incorporates the significant developments in the field since publication of the third edition in 1998, including... New protective groups such as the fluorous family and the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines New techniques for the formation and cleavage of existing protective groups, with examples to illustrate each new technique Expanded coverage of the unexpected side reactions that occur with protective groups New chart covering the selective deprotection of silyl ethers 3,100 new references from the professional literature The content is organized around the functional group to be protected, and ranges from the simplest to the most complex and highly specialized protective groups.
N-Heterocyclic Carbenes in Organocatalysis
Summarizing the emerging field of N-heterocyclic carbenes used in organocatalysis, this is an excellent overview of the synthesis and applications of NHCs focusing on carbon-carbon and carbon-heteroatom bond formation. Alongside comprehensive coverage of the synthesis, characteristics and applications, this handbook and ready reference also includes chapters on NHCs for polymerization reactions and natural product synthesis.
Side Reactions in Organic Synthesis
Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates
Advances in Lithium-Ion Batteries
In the decade since the introduction of the first commercial lithium-ion battery research and development on virtually every aspect of the chemistry and engineering of these systems has proceeded at unprecedented levels. This book is a snapshot of the state-of-the-art and where the work is going in the near future. The book is intended not only for researchers, but also for engineers and users of lithium-ion batteries which are found in virtually every type of portable electronic product.
Computational Biochemistry and Biophysics
Covering theoretical methods and computational techniques in biomolecular research, this book focuses on approaches for the treatment of macromolecules, including proteins, nucleic acids, and bilayer membranes. It uses concepts in free energy calculations, conformational analysis, reaction rates, and transition pathways to calculate and interpret b
Practical Medicinal Chemistry with Macrocycles
Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations
Solvents and Solvent Effects in Organic Chemistry
In most cases, every chemist must deal with solvent effects, whether voluntarily or otherwise. Since its publication, this has been the standard reference on all topics related to solvents and solvent effects in organic chemistry. Christian Reichardt provides reliable information on the subject, allowing chemists to understand and effectively use these phenomena. 3rd updated and enlarged edition of a classic 35% more contents excellent, proven concept includes current developments, such as ionic liquids indispensable in research and industry From the reviews of the second edition: "...This is an immensely useful book, and the source that I would turn to first when seeking virtually any information about solvent effects." —Organometallics
Cannabis Physiopathology Epidemiology Detection
Cannabis Physiopathology and Detection features an outstanding collection of contributions from leading researchers around the world. Papers were presented at the Second International Colloquium on Illicit Drugs, held at the French National Academy of Medicine in April 1992. The book reviews the latest clinical reports describing the effects of cannabis on the brain (imaging techniques, memory and psychomotor performance, cannabis, and schizophrenia), effects on reproduction (male and female), and carcinogenicity. Aspects of detection covered in the volume include methods, results of different testing groups, and legal issues associated with testing and detection. Cannabis Physiopathology and Detection will be an important addition to the reference collections of marijuana researchers, pathologists, government agencies, medical school libraries, and drug testers.
Multicatalyst System in Asymmetric Catalysis
This book introduces multi-catalyst systems by describing their mechanism and advantages in asymmetric catalysis. • Helps organic chemists perform more efficient catalysis with step-by-step methods • Overviews new concepts and progress for greener and economic catalytic reactions • Covers topics of interest in asymmetric catalysis including bifunctional catalysis, cooperative catalysis, multimetallic catalysis, and novel tandem reactions • Has applications for pharmaceuticals, agrochemicals, materials, and flavour and fragrance
