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In the remote mill town of Salmon Falls, Vermont, the dead of winter can feel like death itself. Jobs are scarce, kids are bored, and it sometimes seems there's nothing better to do than drink. But when eighteen-year-old Kyle Nelson and a motley group of friends decide to challenge both the legal drinking age and the local drinking culture with a daring act of civil disobedience, they find there's more to do than they ever imagined. Garret Keizer's gripping novel about young men and women in revolt bears witness to the power of ideas, the bonds of friendship, and the trials of working-class kids on the margins of American society. His story never flinches in the face of those forces that conspire against, but needn't overcome, the resilient spirits of the young.
Divided into two volumes, the book begins with a pedagogical presentation of some of the basic theory, with chapters on biochemical reactions, diffusion, excitability, wave propagation and cellular homeostasis. The second, more extensive part discusses particular physiological systems, with chapters on calcium dynamics, bursting oscillations and secretion, cardiac cells, muscles, intercellular communication, the circulatory system, the immune system, wound healing, the respiratory system, the visual system, hormone physiology, renal physiology, digestion, the visual system and hearing. New chapters on Calcium Dynamics, Neuroendocrine Cells and Regulation of Cell Function have been included.
There is no doubt that if the field of exercise physiology is to make further advancements, the various specialized areas must work together in solving the unique and difficult problems of understanding how exercise is initiated, maintained and regulated at many functional levels, and what causes us to quit. Exercise is perhaps the most complex of physiological functions, requiring the coordinated, integrated activation of essentially every cell, tissue and organ in the body. Such activation is known to take place at all levels - from molecular to systemic. Focusing on important issues addressed at cellular and systemic levels, this handbook presents state-of-the-art research in the field of...
This book contains the manuscripts of the papers delivered at the International Sym posium on Synergetics held at SchloB Elmau, Bavaria, Germany, from April 30 until May 5, 1979. This conference followed several previous ones (Elmau 1972, Sicily 1974, Elmau 1977). This time the subject of the symposium was "pattern formation by dynam ic systems and pattern recognition". The meeting brought together scientists from such diverse fields as mathematics, physics, chemistry, biology, history as well as experts in the fields of pattern recognition and associative memory. When I started this type of conference in 1972 it appeared to be a daring enter prise. Indeed, we began to explore virgin land of...
When new fellows join my lab, I give them some reading materials so that they can orient themselves in their assignment in a new eld. When fellows leave my lab, some after writing their dissertations, I prefer to give them a book as a symbolic present. I was longing for a book that contained something on more or less eve- thing about the islets. At the same time, I wished it contained information as recent as possible. There are a few such books in the market but they are pretty outdated. I started picking islets myself from October 1990, when I joined the Rolf Luft Center, Karolinska Institutet. Over the years my fascination for islet research remained high. Since last year, I felt a strong...
Ontologies are increasingly recognized as essential tools in information science. Although the concepts are well understood theoretically , the practical implementation of ontologies remains challenging. In this book, researchers in computer science, information systems, ontology engineering, urban planning and design, civil and building engineering, and architecture present an interdisciplinary study of ontology engineering and its application in urban development projects. The first part of the book introduces the general notion of ontology, describing variations in abstraction level, coverage, and formality. It also discusses the use of ontologies to achieve interoperability, and to repre...
This book constitutes the refereed conference proceedings of the 28th International Conference on Industrial, Engineering and Other Applications of Applied Intelligent Systems, IEA/AIE 2015, held in Seoul, South Korea, in June 2015. The 73 revised full papers presented were carefully reviewed and selected from 105 submissions. The papers cover a wide range of topics in applied artificial intelligence including reasoning, robotics, cognitive modeling, machine learning, pattern recognition, optimization, text mining, social network analysis, and evolutionary algorithms. They are organized in the following topical sections: theoretical AI, knowledge-based systems, optimization, Web and social networks, machine learning, classification, unsupervised learning, vision, image and text processing, and intelligent systems applications.
This volume constitutes the selected paqpers of the third international conference on Metadata and Semantic Research, MTSR 2009, held in Milan, Italy, in September/October 2009. In order to give a novel perspective in which both theoretical and application aspects of metadata research contribute in the growth of the area, this book mirrors the structure of the Congress, grouping the papers into three main categories: 1) theoretical research: results and proposals, 2) applications: case studies and proposals, 3) special track: metadata and semantics for agriculture, food and environment. The book contains 32 full papers (10 for the first category, 10 for the second and 12 for the third), selected from a preliminary initial set of about 70 submissions.
Mitochondrial diseases are often hard to diagnose. From the time they were first researched without animal models, patients of mitochondrial diseases were of equal interest to both clinical and basic scientists. With the new research done, this book includes updates on the normal structure, function, and molecular biology of the mitochondrial respiratory chain, information on traditional diagnostical methodologies, and an overview of the diagnostic promise of new technologies. The hypermetabolism of Luft disease, although only seen twice, is also studied. There are critical reviews of symptoms and signs associated with syndromes, as well as updates on the genetic defects of either the mitochondrial or the nuclear genome responsible for many disorders.