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This issue of Clinics in Chest Medicine, guest-edited by Dr. Aaron B Waxman and Dr. Inderjit Singh, is focused on Pulmonary Hypertension. Topics discussed in this issue include but are not limited to: Integrative omics to characterize and classify pulmonary vascular disease, Contemporary Pharmacotherapeutic Approach in Pulmonary Arterial Hypertension, Personalized Medicine: The Future Management of Pulmonary Hypertension Requires A New Taxonomy, Sex differences in Pulmonary Hypertension and Pulmonary Hypertension in Pregnancy
A comprehensive and unique review of the bronchoscopy, equipment and quality improvement fundamentals.
The heart and lung are intricately linked. When the heart is affected by disease, the lungs will often show some related pathological or clinical conditions and vice versa. Pulmonary heart disease is by definition a condition when the lungs cause the heart to fail. The left ventricle in combination with the other structures in the “left heart” pumps blood throughout the body. The right ventricle (and structures of the “right heart”) pumps blood to the lungs where it is oxygenated and returned to the left heart for distribution. In normal circumstances, the right heart pumps blood into the lungs without any resistance. The lungs usually have minimal pressure and the right heart easily...
Diagnosing asthma requires knowledge of the multiple conditions that emulate it, and treatment requires addressing factors that modify the disease. This comprehensive, single reference will help practitioners identify and care for co-morbid conditions and improve asthma treatment.
This comprehensive, but practical, reference is an informative guide to the management of acute respiratory problems in the hospital setting. Evaluation of the patient with breathing difficulties is often challenging, since the differential diagnosis is broad and the use of the wrong treatment can exacerbate the problem. This book helps the practising clinician to recognize both common and more unusual causes of respiratory distress in a patient, and assists them in making the correct diagnosis by enhancing their understanding of the application and significance of tests of pulmonary function and pulmonary imaging studies and through improved knowledge of the underlying physiology of acute and chronic respiratory failure that underpins clinical practice in this area. To enhance this 'bench to bedside' approach, authors illustrate their material with helpful management algorithms, and each chapter will conclude with a summary of key points.
This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment. It discusses the definition and classification of these disorders and the epidemiology of pulmonary arterial hypertension (PAH); explores the approach to diagnosis and evaluation via methods such as echocardiography, right heart catheterization, and cardiopulmonary exercise testing; describes the major drug classes used to treat PAH and the cell signaling pathways that they target as well as adjunct and investigative therapies; and highlights special situations that are particularly challenging in the management of PAH. Written by experts in their respective fields, Diagnosis and Management of Pulmonary Hypertension is a valuable resource for pulmonologists, cardiologists, and practitioners in internal medicine and critical care.
This work shows techniques in thoracic surgery from those who developed them. There is broad coverage of lung transplantation and retransplantation; oesophageal problems; small cell lung cancers, and new material on gene therapy, statistics and group clinical trials.
This issue of Clinics in Chest Medicine, guest-edited by Dr. M. Patricia Rivera, is the second of two issues focused on Lung Cancer. Topics discussed in this issue include but are not limited to: Lung Cancer TNM Staging: The 8th Edition; New Surgical Approaches in the Treatment of NSCLC; Alternatives to Surgery for Early Stage Non-Small Cell Lung Cancer: Stereotactic Radiotherapy; Alternatives to Surgery for Early Stage Non-Small Cell Lung Cancer: Thermal Ablation; Advances in the Treatment of Stage III NSCLC; Advances in Treatment of NSCLC: Targeted Therapy; Advances in the Treatment of NSCLC: Immunotherapy; Treatment of Oligometastatic Disease in NSCLC; Management of Malignant Pleural Effusions; Advances in the Treatment of Small Cell Lung Cancer; Palliative Care and the Role of the Primary Care Physician in Lung Cancer Care; Pulmonary Complications of Immunotherapy; and Pulmonary Complications of Chemotherapy and Radiation Therapy.
This book contains contributions of internationally known basic scientists and clinicians with expertise in various aspects of lung injury and repair. This monogram on the pathophysiology and treatment of Acute Lung Injury contains five different sections, each one with contributions from both basic and clinical scientists, outlining existing controversies, an how they can be resolved by future multidisciplinary studies. The various sections discuss: sodium transport and fluid clearance across the normal and injured lungs, the role of the pulmonary surfactant in the pathogenesis and treatment of ARDS, mechanisms and modification of acute and chronic lung injury, ventilatory strategies for the management of acute respiratory distress syndrome and nitric oxide: friend or foe.
Forty-seven international specialists contribute 23 chapters documenting recent progress made in the research of the acute respiratory distress syndrome (ARDS) and clinical acute lung injury (ALI) at the molecular, cellular, and physiological levels, and current pharmacological and ventilatory appro