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The Romaunt of the Rose
The Romaunt of the Rose translates in abridged form a long dream vision, part elegant romance, part rollicking satire, written in France during the thirteenth century. The French original, Le Roman de la Rose, had a profound influence on Chaucer, who says he translated the work. From the sixteenth century to the mid-nineteenth, scholars assumed that the Romaunt comprised large fragments of that translation. Subsequent debates have divided the Romaunt into two or three segments, and proffered arguments that Chaucer was responsible for one or more of them, or for none. The current consensus is that he almost certainly wrote the first 1,705 lines. Charles Dahlberg’s edition of the Romaunt provides a full summary of scholarship on the question of authorship as well as other important topics, including a useful survey of the influence of the French poem on Chaucer.
The Dictes and Sayings of the Philosophers. A Facsimile Reproduction of the First Book Printed in England by William Caxton, in 1477
Reprint of the original, first published in 1877.
Genome Instability in Cancer Development
Research over the past decades has firmly established the genetic basis of cancer. In particular, studies on animal tumour viruses and chromosome rearrangements in human tumours have concurred to identify so-called ‘proto-oncogenes’ and ‘tumour suppressor genes’, whose deregulation promotes carcinogenesis. These important findings not only explain the occurrence of certain hereditary tumours, but they also set the stage for the development of anti-cancer drugs that specifically target activated oncogenes. However, in spite of tremendous progress towards the elucidation of key signalling pathways involved in carcinogenesis, most cancers continue to elude currently available therapies....
The British Poets
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DNA Repair and Mutagenesis
An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.
