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The success of a scientific workshop depends on a delicate blend of many types of ingredients. Most important is to select a provocative topic which is at the forefront of a current investigative study. Coupled together with a relatively small but distinguished group of active research scientists known for their continued record of contributing significant findings, one has the firm foundation for an exciting and rewarding investment of time and effort. This was the setting for the first workshop organized by the European Association for Veterinary Pharmacology and Toxicology. Ruminants have been domesticated for many centuries and have served mankind as a source of dairy products, meat, woo...
First multi-year cumulation covers six years: 1965-70.
Magnetic resonance imaging has already become a most valuable imaging modality in the diagnostic work-up of musculoskeletal neoplasms. While high accuracy of MRI for staging purposes has been proven, we will focus in this monograph on the characterization of primary bone and soft tissue tumors by MRI. The major purpose of this monograph is to provide an atlas of magnetic resonance features of primary bone and soft tissue tumors for radiologists, orthopedic surgeons and physiotherapists. The results presented are based on investigations of 94 primary bone and soft tissue tumors and mimicking conditions by magnetic resonance imaging. Although the scale of the material allows for statistical ha...
This is the first comprehensive volume to look at the importance of short-chain fatty acids in digestion, the function of the large intestine and their role in human health. Short-chain fatty acids are the major product of bacterial fermentation of dietary carbohydrates in the human and animal large intestine. They represent the major end products of digestive processes occurring in the caecum and large intestine. As such, they form an important dietary component and it is increasingly recognised that they may have a significant role in protecting against large bowel cancer and in metabolism. Prepared by an international team of contributors who are at the forefront of this area of research, this volume will be an essential source of reference for gastroenterologists, nutritionists and others active in this area.
This Community meeting has been organised, since over the past 15 years in different countries of Western Europe including Scandinavia, a lot of research has been directed to the summer mastitis problem. Summer mastitis in cattle is a well known disease which, because of its abruptness and the difficulties concerned in defining the predisposing factors and the pathogens involved, is hard to control. Moreover, as it is anticipated that in the transmission of the bacteria one or more dipterans are involved, the complexity in defining the disease and hence co-ordinating our scientific knowledge in relation to practical control was stimulus enough for this workshop to be organised. Our aims can ...
A seminar in the Community Programme for the Coordination of Agricultural Research, held in Brussels, Belgium, April 7-9, 1987
Parkinson's disease is the only neurodegenerative disorder for which the major pathological and biochemical defects have been identified. But why dopamine-containing cells in the substantia nigra die in Parkinson's disease remains a mystery. Similarly, the changes in basal ganglia output pathways which lead to the onset of motor disability and the occurrence of L-DOPA induced dyskinesia remain unclear. While treatment for the symptoms of Parkinson's disease is available, nothing can presently be done to stop the disease progressing. A molecular approach to Parkinson's disease is unraveling genetic factors responsible for inducing the onset of nigral cell degeneration or for making individual...
Noradrenergic Mechanisms in Parkinson's Disease examines fundamental and clinical evidence explaining the progression of the disease. Featuring contributions from acknowledged international experts in the field, this book defines ideopathic Parkinson's disease and covers such topics as the alterations in Parkinson's disease, norepinephrine-dopamine interactions, noradrenergic control of striatal dopamine release, glial cells as targets of the central noradrenergic systems, and a theory regarding noradrenergic mechanisms in Parkinson's disease. New directions for research on Parkinson's disease are also explored.
This publication contains the proceedings of a seminar held in Brussels on November 8-9, 1988. The title of the seminar was "Reducing the costs of disease by improving resistance through genetics". The seminar was held as an activity of the Community Programme for the Coordination of Agricultural Research, 1984-1988. Costs of disease depend on losses caused by morbidity, mortality and production decreases and on the costs of preventive measures including vaccination and medication. Production losses often contribute a major portion to the total costs. To reduce costs of disease preventive measures like vaccination, preventive medication and hygienic procedures are applied. Genetic resistance is an attractive preventive measure because of its consistent nature in the next generations, because it precludes veterinary services and because there are no side-effects. Constraints are the long term investment, relatively slow progress per generation (in combination with production traits) and the considerable lack of knowledge about inheritance of resistance mechanisms in farm animals.
Effective new treatments of heart disease are based on a refined understanding of cellular function and the heart's response to environmental stresses. Not surprisingly therefore, the field of experimental cardiology has experienced a phase of rapid expo nential growth during the last decade. The acquisition of new knowledge has been so fast that textbooks of cardiology or textbooks of cardiovascular physiology are often hard-pressed to keep up with the most important conceptual advances. Witness the explosive increase in knowledge about signaling pathways of cardiac growth, transcrip tional regulation of cardiac metabolism, hormonal signaling, and the complex responses of the heart to ische...