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Learning from the COVID-19 Pandemic
  • Language: en
  • Pages: 334

Learning from the COVID-19 Pandemic

  • Type: Book
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  • Published: 2023-08-24
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  • Publisher: CRC Press

COVID-19 is a highly contagious viral illness caused by severe acute respiratory syndrome SARSCoV-2. It has had a devastating effect on the world’s demographics with high morbidity and mortality worldwide. After the influenza pandemic of 1918, it has emerged as the most consequential global health crisis. After the first cases of this predominantly respiratory viral illness were first reported in Wuhan, Hubei Province, China, in late December 2019, SARS-CoV- 2 rapidly disseminated across the world in a short span of time, compelling the World Health Organization (WHO) to declare it a global pandemic on March 11, 2020. The outbreak of COVID-19 has proven to be a worldwide unprecedented disa...

Biomedical Translational Research
  • Language: en
  • Pages: 493

Biomedical Translational Research

The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.

Biomedical Research, Medicine, and Disease
  • Language: en
  • Pages: 665

Biomedical Research, Medicine, and Disease

  • Type: Book
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  • Published: 2023-04-04
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  • Publisher: CRC Press

Biomedical research is the first step towards the creation of new medications and treatments that help to manage different types of health conditions and diseases. The prevention and cure of diseases would be practically impossible without such type of research. Although the drug discovery and development processes are far too costly, time-consuming, prone to failure, and have low success rate, today the term "translational research or medicine" seems to have become trendy, yet it is insufficient. The present book is a sincere attempt by dedicated researchers to convey the importance of translational biomedical research, medicine, and disease, primarily, basic and clinical difficulties in th...

Comprehensive Textbook on Vitiligo
  • Language: en
  • Pages: 555

Comprehensive Textbook on Vitiligo

  • Type: Book
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  • Published: 2020-09-16
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  • Publisher: CRC Press

Vitiligo is a disorder having a significant impact in dark-skinned individuals. Along with the historical, cultural, and psychological aspects of the disease the multifactorial pathogenesis of this disorder is discussed in detail with special emphasis on the newer hypotheses proposed in the causation. Descriptions of the clinical aspects of the disease are supplemented with clinical photographs covering the latest therapeutic and surgical treatment options. Nonconventional treatments such as cosmetic camouflage and tattooing are also discussed. Topics of controversy such as the role of diet, patient selection for surgery, and so on, are covered in depth. Key Features Discusses the recent advances in treatment Evidence-based approach Quality of life and psychological aspects covered Nonconventional treatment options included with practical tips on vitiligo surgery Controversial topics covered

Role of Microbes in Sustainable Development
  • Language: en
  • Pages: 713

Role of Microbes in Sustainable Development

This book examines the role of human microbiome in human health and diseases. The initial chapters present tools for genetic manipulation of gut microbiota and the therapeutic applications of engineered microbiota. They discuss the interaction between human microbiota and host in defining the prominent role of microbes in the development and progression of major human diseases. The book also summarizes the current applications and trends for the development, production and analytical characterization of recombinant therapeutic proteins in microbial systems. It also reviews the role of microbes in the production of vaccines and antibiotics. Further, the book presents bacterial products, inclu...

Molecular Biomarkers in Cancer
  • Language: en
  • Pages: 530

Molecular Biomarkers in Cancer

This book is focused on the history of cancer research. It follows the evolution of techniques and their applications in the diagnosis, treatment and management of cancer, from genetics to omics and finally the discovery of biomarkers. The book also discusses the present scenario in cancer development and management, and describes the importance of understanding cancer biology using microRNA, novel sequencing, and machine-learning approaches to determine DNA mutations. The book will be of value to students, research scholars, scientists, and innovators.

Drug Repurposing for Emerging Infectious Diseases and Cancer
  • Language: en
  • Pages: 664

Drug Repurposing for Emerging Infectious Diseases and Cancer

​This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and in silico approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning.

Sujata Bodhankar
  • Language: en
  • Pages: 50

Sujata Bodhankar

  • Type: Book
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  • Published: 2024-03-27
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  • Publisher: Pencil

In "Sujata Bodhankar: An Extraordinary Grandmother's Tale of Love and Resilience," embark on a heartfelt journey through the life of Sujata Bodhankar, a remarkable woman whose unwavering strength and boundless love have left an indelible mark on those around her. From her early years as a plant biologist and teacher to her later roles as a celebrated author and loving grandmother, Sujata's story is one of resilience, courage, and unwavering faith. Through the eyes of her granddaughter, experience the profound impact of Sujata's teachings on spirituality and science, and discover the profound connection between love, loss, and the human spirit. With poignant storytelling and heartfelt emotion, this book is a tribute to the extraordinary life and enduring legacy of Sujata Bodhankar.

Biomarkers in Cancer Detection and Monitoring of Therapeutics
  • Language: en
  • Pages: 400

Biomarkers in Cancer Detection and Monitoring of Therapeutics

Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision ...

Environmental Studies and Climate Change
  • Language: en
  • Pages: 629

Environmental Studies and Climate Change

  • Type: Book
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  • Published: 2022-12-13
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  • Publisher: CRC Press

Currently, anthropogenic activities have caused unprecedented destruction of the environment at alarming rates, leading to undesirable alterations in air, land, and water. The process of environment degradation has been accelerated by industrial processes, which result in waste as well as over-consumption of natural resources. The ecological balance has been disturbed, and resources have shrunk. All this has resulted in climate change, which has emerged as a major concern in the 21st century. Changes in the environment are driven by demand for energy, water, and food to raise the standard of living. These are also responsible for climate change, with contributions from deforestation and CO2 ...