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NHS Next Stage Review
Incorporating HC 937-i to iii, session 2007-08. The final report of the Next Stage Review, led by Lord Darzi, published as "High quality care for all" in June 2008 (Cm. 7432, ISBN 9780101743228)
MICROSCOPIC HAEMATOLOGY
An invaluable aid for professional scientists and students in diagnostic haematology laboratories and teaching institutions. Uniquely designed for use beside the microscope, this atlas describes the subtle changes which differentiate and allow recognition of haemopoietic cells during normal development and then presents in full colour the features which lead to the diagnosis of blood disorders. All common and virtually all rare disorders are magnificently portrayed.
Cytometric Analysis of Cell Phenotype and Function
Flow cytometry and laser scanning cytometry are increasingly used in clinical and research settings due to improvements in instrument design and computing power and the increased availability of fluorescent agents. This book provides a comprehensive introduction to the theory and clinical applications of these techniques in the assessment of cell phenotype and function. With an emphasis on clinical relevance, the book presents the principles and potential of cytometry in the analysis of phenomena including cell-mediated cytotoxicity, metabolic burst, phagocytosis, cell-cell aggregation, receptor shedding, and apoptosis. The volume guides the reader through data interpretation, quality control procedures, pitfalls, and problems.
Postgraduate Haematology
The textbook of choice for trainees and practitioners in haematology Over five editions Postgraduate Haematology has built a reputation as an extremely practical, user-friendly, reliable source of information for examination preparation and clinical practice. Completely revised to reflect the latest research in the field, this edition continues to provide trainees with up-to-date knowledge on the pathogenesis, clinical and laboratory features, and management of blood disorders. It covers the significant advances which have occurred in the application of cytogenetics and molecular genetics in the diagnosis, classification and understanding of haematological disorders. Coupled with the experti...
Making Wicked Problems Governable?
The book analyses the developments of inter-organizational networks in the UK National Health Service during the New Labour period, combining empirical case studies from various policy arenas (clinical genetics, cancer networks, sexual health networks, and long term care) with a theoretically informed analysis.
NICE
It may seem as if the National Institute of Health and Care Excellence (NICE) has always been part of the UK’s health and social care landscape. But this fascinating book charts the evolution of NICE from its origins 25 years ago, as well as how this development illustrates many of the key themes effecting health care today. In a period of rapid medical and technological advance, NICE has been both a gatekeeper to ensure that health care resources are spent where they are needed most, and a promoter of patient access to the best new technologies. Through a detailed history, the authors show how NICE’s remit grew from health care to public health to social care, advancing the use of evide...
Clinical Academic Medicine
Academic medicine in the UK faces serious and immediate problems. It is essential that that the number of clinical academics in all disciplines be increased in order to teach the doctors of the future, and to maintain high-quality medical research which can translate scientific and clinical discoveries into real benefits for patients. This report brings together all 14 Medical Royal Colleges to consider how best to address these issues and to propose solutions. Part 1 considers the challenges that are common to all the Colleges, and makes recommendations designed to increase the recruitment and retention of academic staff, by making an academic career path a more attractive and achievable option.
Antibody Therapy
This practical manual, written by well-known experts, reviews current indications for the use of IgG concentrates and some other modern immunomodulators and provides fundamental information on present-day immunomodulation in patients (and mice). The book opens by tracing the transition from IgG substitution to IgG immunomodulation and providing expert updates on immunomodulatory indications in autoimmune and inflammatory disorders, including hematologic, neurologic, dermatologic, and other diseases. Basic aspects of IgG concentrates, including methods of production, safety, currently available products, and mechanisms of action, are then discussed. An entire chapter is devoted to the different aspects of immunomodulatory IgG treatment in the bleeding disorder immune thrombocytopenia (ITP). Finally, the transition from polyclonal to monoclonal antibody (mAb) treatment is addressed in detail, covering mAb development, methods, mechanisms of action, adverse effects, and more. Particular attention is paid to the example of anti-CD20 (B-cell) antibody.
Journal of the National Cancer Institute
Each issue is packed with extensive news about important cancer related science, policy, politics and people. Plus, there are editorials and reviews by experts in the field, book reviews, and commentary on timely topics.
Medical Specialisation at the London Hospital
The development of specialty skills in medical and surgical practice in the late 19th and in the 20th century transformed medical practice. For the first time, a patient could visit a doctor with the expectation of an accurate diagnosis and effective treatment. Disease prevention became a realistic proposition. Traditional practice methods became obsolescent, but a yearning for generalist medical wisdom and respect continued until the 2nd World War disrupted progress. In the 19th century, the London Hospital was remarkably open to new ideas, and the Chairman of the Board, Viscount Knutsford, was a master fundraiser. Investment in novel facilities and staff, including the establishment of special departments, and consequent changes in clinical practice led to a growing national and international reputation in clinical practice and education. Specialty skills defined innovations, both in hospital and family practice. More recently, merging St Bartholomew’s, the Royal London Hospital and other hospitals has reactivated the advance of specialism.
