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The Diagnosis and Treatment of Male Infertility
This case-based guide is written from the clinician's perspective, dealing with a defined male infertility problem, tracing the actual clinical pathway arriving at the diagnosis, and discussing the treatment options and the likely outcome. Rather than focusing on excessive theoretical details, each chapter presents a unique clinical vignette or scenario, the relevant aspects of which are followed throughout the entire chapter, correlating specific fertility issues with clinical findings, describing treatment options, prognoses and procedures (when indicated), and concluding with practical clinical pearls. Opening with chapters describing current diagnoses of male infertility and semen analys...
Manual of Embryo Culture in Human Assisted Reproduction
Provides practical guidance for the optimal organization and management of an IVF laboratory for successful embryo culture.
Andrological Evaluation of Male Infertility
This state-of-the-art laboratory manual includes 20 clinical protocols used daily for the investigation of the infertile male, presented with easy to understand, step-by-step methodology. The protocols are arranged from routine to advanced laboratory procedures common to clinical practice, including computer-assisted semen analysis, sperm preparation for IUI by density gradient and swim-up, sperm cryopreservation, and sperm DNA fragmentation test by TUNEL method, among others. The methodology in each protocol follows best practice guidelines made clearer by professionally hand-drawn illustrations covering most of the important steps and equipment. The authors, hailing from the world-renowned Andrology Center at Cleveland Clinic, have over 50 years of combined first-hand experience in managing very busy diagnostic and research facilities in male infertility and andrology. The book will be an indispensable resource for thousands of laboratory technologists, clinicians and reproductive professionals (andrologists, embryologist, etc.) engaged in the diagnosis and management of infertile men around the world.
A Clinician's Guide to Sperm DNA and Chromatin Damage
This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors. Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natur...
Male Infertility
A groundbreaking contribution to the literature now in its revised and expanded second edition, this textbook offers a comprehensive review of diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based textbook incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind guide to treatment strategies for male infertility and beyond. While this new edition is primarily designed as a reference for students and residents in reproductive medicine and andrology, it will be equally useful as well for professionals in urology, reproductive endocrinology, embryology, and research fields who are interested in the role that...
Men's Reproductive and Sexual Health Throughout the Lifespan
A practical and integrated approach to male reproductive and sexual health and how to manage patients with infertility and sexual dysfunction. The text includes a comprehensive evaluation of fertility difficulties, sexual dysfunction, hormone management in men, prostate health, and testicular pain, as well as mental health and vitality.
Practical Guide in Andrology and Embryology
Part of a new series on reproductive medicine, this book is a complete guide to andrology and embryology. Divided into 38 chapters, the text begins with in depth discussion on male infertility covering sperm function tests, screening, sperm selection for ART, sperm banking, and various causes of male infertility. The second part of the book examines assisted reproductive techniques in male infertility, frozen embryo transfer, oocyte and embryo cryopreservation, third party reproduction, and more. The book presents the latest advances in the field and each chapter includes key points and references for further reading. Clinical photographs, diagrams and tables further enhance the comprehensive text. Other titles in the series include: Practical Guide in Infertility, Practical Guide in Reproductive Surgery and Practical Guide in Assisted Reproductive Technology. Key points Comprehensive guide to andrology and embryology Part of new series on reproductive medicine Covers numerous ART procedures for male infertility Chapters include key points and detailed references for further reading
The Expert Guide to Fertility
The essential guide to understanding fertility and improving your pregnancy chances. The journey to fertility can be daunting and filled with obstacles. In The Expert Guide to Fertility, OB-GYNs Joseph S. Sanfilippo, MD, MBA, and Aarti Kumar, MD, offer the information you need in your journey to achieve pregnancy. They provide an overview of the human reproductive system, describe issues that may impede conception, and explain various medical, surgical, and lifestyle interventions shown to improve one's chances of becoming pregnant. Sanfilippo and Kumar offer important information on: • A broad variety of assisted reproductive technologies, including in vitro fertilization • Diagnostic tests and what to expect throughout your fertility journey • Fertility-preserving options for people diagnosed with cancer and people with recurrent miscarriages, polycystic ovaries, a low egg supply, or endometriosis • Fertility options for LGBTQ+ readers, single parents, and military personnel • Adoption, egg and sperm donation, and egg freezing procedures • Financing options, including tips for working with health care insurers
Antioxidants in Andrology
This book focuses on the use of various molecules with antioxidant properties in the treatment of major male genital tract disorders, especially male infertility, erectile dysfunction, and accessory gland infection. The coverage also includes discussion of pathophysiology, the molecular basis of male infertility, and the rationale for use of antioxidants, with particular attention to coenzyme Q10 and carnitine. Oxidative stress occurs when the production of reactive oxygen species, including free radicals, exceeds the body’s natural antioxidant defences, leading to cellular damage. Oxidative stress is present in about half of all infertile men, and reactive oxygen species can produce infertility both by damaging the sperm membrane, with consequences for sperm motility, and by altering the sperm DNA. There is consequently a clear rationale for the use of antioxidant treatments within andrology, and various in vitro and in vivo studies have indicated that many antioxidants indeed have beneficial impacts. In providing a detailed and up-to-date overview of the subject, this book will be of interest to both practitioners and researchers in andrology, endocrinology, and urology.
