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Quantitative Biology: Dynamics of Living Systems
With the emergence of Systems Biology, there is a greater realization that the whole behavior of a living system may not be simply described as the sum of its elements. To represent a living system using mathematical principles, practical quantities with units are required. Quantities are not only the bridge between mathematical description and biological observations; they often stand as essential elements similar to genome information in genetics. This important realization has greatly rejuvenated research in the area of Quantitative Biology. Because of the increased need for precise quantification, a new era of technological development has opened. For example, spatio-temporal high-resolu...
Systems Biology
This book explores Systems Biology as the understanding of biological network behaviors, and in particular their dynamic aspects, which requires the utilization of mathematical modeling tightly linked to experiment. A variety of approaches are discussed here: the identification and validation of networks, the creation of appropriate datasets, the development of tools for data acquisition and software development, and the use of modeling and simulation software in close concert with experiment.
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Introduction to Systems Biology
This book provides an introductory text for undergraduate and graduate students who are interested in comprehensive biological systems. The authors offer a broad overview of the field using key examples and typical approaches to experimental design. The volume begins with an introduction to systems biology and then details experimental omics tools. Other sections introduce the reader to challenging computational approaches. The final sections provide ideas for theoretical and modeling optimization in systemic biological researches. The book is an indispensable resource, providing a first glimpse into the state-of-the-art in systems biology.
MULTICORE SYSTEMS ON-CHIP
Conventional on-chip communication design mostly use ad-hoc approaches that fail to meet the challenges posed by the next-generation MultiCore Systems on-chip (MCSoC) designs. These major challenges include wiring delay, predictability, diverse interconnection architectures, and power dissipation. A Network-on-Chip (NoC) paradigm is emerging as the solution for the problems of interconnecting dozens of cores into a single system on-chip. However, there are many problems associated with the design of such systems. These problems arise from non-scalable global wire delays, failure to achieve global synchronization, and difficulties associated with non-scalable bus-based functional interconnect...
