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New Horizons in Predictive Toxicology
The sophistication of modelling and simulation technologies have improved dramatically over the past decade and their applications in toxicity prediction and risk assessment are of critical importance. The integration of predictive toxicology approaches will become increasingly necessary as industrial chemicals advance and as new pharmaceuticals enter the market. In this comprehensive discussion of predictive toxicology and its applications, leading experts express their views on the technologies currently available and the potential for future developments. The book covers a wide range of topics including in silico, in vitro and in vivo approaches that are being used in the safety assessmen...
New Horizons in Predictive Drug Metabolism and Pharmacokinetics
Drug metabolism, pharmacokinetics and toxicokinetics as determinants of drug attrition and the safety of xenobiotics are critically important. This book presents a comprehensive treatise on the current issues and challenges facing drug metabolism and pharmacokinetics. Readers will find a thorough exploration of their predictive role in impacting drug discovery and development and in improving the success rate and safety assessment of pharmaceuticals and industrial or occupational chemicals. Chapters not only focus on the current state of art, with distinct examples, but on future needs and approaches likely to improve our prediction of potential human risk. Discussions of critical properties...
The Discovery of the Ark of the Covenant
British history records that there were tow major migrations form the near east into Britain in antiquity. One was the fleet migration form Syria led by Albyne around 1560 BC, and the other was the second fleet migration from the Trojan Dardanelles areas in Western Turkey led by Brutus around 504 BC. Ancient alphabet inscriptions and other tangible and written records show that the second migration was that of the Ten Tribes of Israel. The same ancient Alphabet is found all the way along the British migration routes form Palestine, to Assyria, through Asia Minor to the Aegean and to Etruscan Italy and Rhaetian Switzerland. In Britain the Ten Tribes were known as the Khumry. This research beg...
New Horizons in Predictive Drug Metabolism and Pharmacokinetics
This book thoroughly explores the predictive role of drug metabolism and pharmacokinetics in drug discovery and in improving success rates and safety assessments of chemicals.
Model-Based Engineering for Complex Electronic Systems
In the electronics industry today consumer demand for devices with hyper-connectivity and mobility has resulted in the development of a complete system on a chip (SoC). Using the old ‘rule of thumb’ design methods of the past is no longer feasible for these new complex electronic systems. To develop highly successful systems that meet the requirements and quality expectations of customers, engineers now need to use a rigorous, model-based approach in their designs. This book provides the definitive guide to the techniques, methods and technologies for electronic systems engineers, embedded systems engineers, and hardware and software engineers to carry out model- based electronic system ...
Poetical Works
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To Heal and Not to Hurt
'The mark of a healthy and authentically Christian community is not large numbers, inspiring worship, or dogmatic theology, but the way in which power is exercised within it.'In recent years churches have found themselves all but overwhelmed by safeguarding concerns and allegations of abuse. Rosie Harper and Alan Wilson - who share almost seventy years of pastoral ministry - have listened with increasing dismay to many of the people who have had seriously damaging experiences within the Church. To Heal and Not to Hurt presents 15 narrative examples of these experiences, and examines the deep institutional roots of the abusive attitudes that caused them and the Church's often equally damaging responses. It concludes with the suggestion of a calm, reasoned, and practical basis on which the Church could shape a more adequate and sustainable policy of prevention and response.
