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Proteins
Formation of transmembrane pores is a very effective way of killing cells. It is thus not surprising that many bacterial and eukaryotic toxic agents are pore-forming proteins. Pore formation in a target membrane is a complex process composed of several steps; proteins need to attach to the lipid membrane, possibly aggregate in the plane of the membrane and finally form a pore by inserting part of the polypeptide chain across the lipid bilayer. Structural information about toxins at each stage is indispensible for the biochemical and molecular biological studies that aim to - derstand how pores are formed at the molecular level. There are currently only two Staphylococcus aureus and hemolysin...
Healing the Body Politic
Incorporating investigative journalism and drawing on interviews with participants and leaders, Sandy Smith-Nonini examines the contested place of health and development in El Salvador over the last two decades. Healing the Body Politic recounts the dramatic story of radical health activism from its origins in liberation theology and guerrilla medicine during the third-world country's twelve-year civil war, through development of a remarkable "popular health system," administered by lay providers in a former war zone controlled by leftist rebels. This ethnography casts light on the conflicts between the conservative Ministry of Health and primary health advocates during the 1990s peace proce...
Seeking Social Democracy
The first full-length treatment of Ed Broadbent’s ideas and remarkable seven-decade engagement in public life Part memoir, part history, part political manifesto, Seeking Social Democracy offers the first full-length treatment of Ed Broadbent’s ideas and remarkable seven-decade engagement in public life. In dialogue with three collaborators from different generations, Broadbent leads readers through a life spent fighting for equality in Parliament and beyond: exploring the formation of his social democratic ideals, his engagement on the international stage, and his relationships with historical figures from Pierre Trudeau and Fidel Castro to Tommy Douglas, René Lévesque, and Willy Bran...
Digital Activism, Community Media, and Sustainable Communication in Latin America
This book brings together academic and activist work on community media, feminist, decolonial, and Indigenous perspectives to digital activism, including Free and Open Communication in Latin America. The essays in this collection speak to major changes over the past decade that are reshaping digital media uses and practices. The case studies presented here question many commonly held assumptions around global media ownership, sustainability, and access relevant to countries beyond Latin American contexts.
Journalism and Safety
This volume presents key international research on journalism and safety with a focus on conceptual, global, and transnational approaches, as well as conflict, challenges, and consequences for democracy. It offers an overview of the latest research and ongoing developments in the field of journalism and safety and speaks to the ways in which digital developments have worsened the risks surrounding journalists, with online harassments, security breaches, surveillance and so forth challenging their safety like never before. The first of two volumes, this book comprises a handpicked collection of cutting-edge research articles authored by distinguished international scholars. The chapters in th...
Insecticidal Proteins and RNAi in the Control of Insects
Insecticidal Proteins and RNAi in the Control of Insects, Volume 65 in the Advances in Insect Physiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Insecticidal RNAi delivered as biopesticide, Cry toxins, Vip3 insecticidal proteins: Structure and Mode of Action, New plant/other bacteria toxins, Engineered insecticidal proteins, Resistance to insecticidal proteins, and Photorhabdus toxins across Gram-negative bacteria. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Insect Physiology series - Updated release includes the latest information on the Insecticidal proteins and RNAi in the control of Insects
Selected Topics in Migration Studies
This book provides a collection of key papers about migration, focusing on multiple aspects of international and internal migration in various times and places. Because migration has been such an important part of global peopling, the book contains synopses of major geographic movements from ancient and early history as well as the present. It includes material from anthropology, archaeology, criminology, demography, economics, ethnic studies, geography, health sciences, history, law, public policy, political science, psychology, and sociology. By providing a treatment of migration that is multifaceted, comparative, and multi-disciplinary, it offers not only a basis for conceptualizing broad features of migration and their changes, but also one for discerning the formal and informal policy auspices that have influenced migration. The book thus constitutes a significant resource for students, teachers, practitioners, scholars, and researchers interested in or working on aspects of migration in any field. It should be particularly useful for people seeking information and knowledge about migration from fields other than their own.
Integrated Pest Management and Pest Control
Integrated Pest Management is an effective and environmentally sensitive approach that relies on a combination of common-sense practices. Its programs use current and comprehensive information on the life cycles of pests and their interactions with the environment. This information, in combination with available pest control methods, is used to manage pest damage by the most economical means and with the least possible hazard to people, property, and the environment.
Women Winning Office
When Peggy Nash first decided to run for elected office, she had no idea where to start, who to contact, or what the rules were. For those who are underrepresented in political life, politics can seem like a secret society designed to shut them out. Women Winning Office is a practical handbook for activist women on how to open doors and take their place in the political process. Find out how to build a team, get nominated, inspire volunteers, and canvass voters. Nash draws on her experience in five federal campaigns, as well as the stories of many inspiring Canadian women who have run for office at all levels of government. Some succeeded; some did not. Some faced difficult and painful experiences. Every one of them would do it again. To make real progressive change, we need to change not only who gets elected in Canada, but how our democracy functions. If you want to find out how to take your desire for a better world into elected office, this book is for you.
Pore-forming Peptides and Protein Toxins
Pore-forming proteins and peptides play a central role in bacterial pathogenesis, the immune response, venomous attack, and innate immunity. Pore-forming Peptides and Protein Toxins describes how natural and synthetic peptides and toxins form pores and ionic channels that cause cell membrane collapse and cell death. Written by researchers from around the world, it discusses such topics as the channel-forming properties of Helicobacter pylori and the role of amyloid peptide channels in the development of amyloid diseases. This text provides a multidisciplinary approach to understanding the basic principles and cellular mechanisms of the actions of toxins and their potential use as research tools.
