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Fundamentals of Brain Network Analysis
Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain...
Artificial Intelligence for Medicine
The use of artificial intelligence (AI) in various fields is of major importance to improve the use of resourses and time. This book provides an analysis of how AI is used in both the medical field and beyond. Topics that will be covered are bioinformatics, biostatistics, dentistry, diagnosis and prognosis, smart materials, and drug discovery as they intersect with AI. Also, an outlook of the future of an AI-assisted society will be explored.
Pieces of Light
Shortlisted for the Royal Society Winton Prize 2013 and the 2013 Best Book of Ideas Prize. Memory is an essential part of who we are. But what are memories, and how are they created? A new consensus is emerging among cognitive scientists: rather than possessing a particular memory from our past, like a snapshot, we construct it anew each time we are called upon to remember. Remembering is an act of narrative as much as it is the product of a neurological process. Pieces of Light illuminates this theory through a collection of human stories, each illustrating a facet of memory's complex synergy of cognitive and neurological functions. Drawing on case studies, personal experience and the latest research, Charles Fernyhough delves into the memories of the very young and very old, and explores how amnesia and trauma can affect how we view the past. Exquisitely written and meticulously researched, Pieces of Light blends science and literature, the ordinary and the extraordinary, to illuminate the way we remember and forget.
Magnetic resonance imaging of disturbed brain connectivity in psychiatric illness
The widespread application of brain imaging to the study of psychiatric disorders has led to a revolution in our understanding of the neural basis of psychiatric illness. In particular, the advent of magnetic resonance imaging (MRI) has provided an unprecedented capacity for quantifying diverse aspects of brain structure and function in vivo, and has been used to identify brain changes associated with the full spectrum of psychopathology. With respect to major psychiatric disorders, it is now abundantly clear from this literature that focal brain dysfunction is rare. Rather, most disorders are associated with abnormalities in large-scale networks of spatially distributed and interconnected b...
The Creative Advantages of Schizophrenia
The aphorism that madness and creative genius are opposing sides of the same coin predates contemporary psychiatry and has existed since the time of the great Stagirite Aristotle. Schizophrenia is one mental disorder intimately linked with creative thinking and achievement. There is no shortage of eminent scientists, thinkers, writers, artists, composers, and political activists tentatively theorized to have precariously balanced the great divide between the demons of schizophrenia and the muses of creative illumination, including Rene Descartes, Emanuel Swedenborg, John Forbes Nash, Leonardo da Vinci, and Joan of Arc, to name but a few. However, is that association veracious in an empirical sense? If it is, how exactly are schizophrenia and creative illumination related? Using new empirical findings, this book sheds new light upon the age-old assumption and goes further still in explaining how creative potential with world-fashioning powers can be channelled in individuals with this diagnosis. Mental health practitioners will find this book both intriguing and useful.
The Recognition and Management of Early Psychosis
This new edition describes a stage-specific model highlighting the risk, the clinical and biological factors present during the development of psychotic illness, and the best treatments available for each of these stages. Guides practitioners and researchers in the adoption of carefully planned management strategies fully integrating treatment with prevention.
Biological Network Analysis
Biological Network Analysis: Trends, Approaches, Graph Theory, and Algorithms considers three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN), and Human Brain Connectomes. The book's authors discuss various graph theoretic and data analytics approaches used to analyze these networks with respect to available tools, technologies, standards, algorithms and databases for generating, representing and analyzing graphical data. As a wide variety of algorithms have been developed to analyze and compare networks, this book is a timely resource. Presents recent advances in biological network analysis, combining Graph Theory, Graph Analysis, and various network models Discusses three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN) and Human Brain Connectomes Includes a discussion of various graph theoretic and data analytics approaches
Integrative Neuroscience and Personalized Medicine
This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavio...
Biological Research on Addiction
Biological Research on Addiction examines the neurobiological mechanisms of drug use and drug addiction, describing how the brain responds to addictive substances as well as how it is affected by drugs of abuse. The book's four main sections examine behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process. This volume is especially effective in presenting current knowledge on the key neurobiological and genetic elements in an individual's susceptibility to drug dependence, as well as the processes by which some individuals proceed from casual drug use to drug dependence. Biological Research on Addiction is one of...
Creativity in Large-Scale Contexts
A new model for smarter creativity
