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This is the first in a two-volume, comprehensive treatment of the methodologies used in researching the Zebrafish, an emerging vertebrate model system. The text includes discussions on development, genetic methodologies, and model applications. Key Features * Details state-of-the-art zebrafish protocols in a single-source reference * Presents methods and reagents in user-friendly format * Delineates critical steps and pitfalls of he procedures * Illustrates techniques with full-color plates * Summarizes many new and interesting developmental mutants * Includes appendices with strain information and a compendium of zebrafish World Wide Web sites * Relevant to clinicians interested in vertebrate models of human congenital diseases
Emmanuel Joseph Sieyès occupies a prominent place within the history of political thought. He stands at the forefront of both the discourses on human rights and on democratic constitutionalism. And yet, because of his theory of the constituent power he holds a somewhat ambivalent reputation as an advocate of permanent revolution. This state of reception is largely due to the fact that the better part of his work has hitherto not been edited outside of France. The edition Emmanuel Joseph Sieyès: The Essential Political Writings proposes to fill out this desideratum. It seeks to portray Sieyès, against the backdrop of an enlarged textual corpus, as a moderate proponent of the constitutional State.