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M1/M2 Macrophages: The Arginine Fork in the Road to Health and Disease
Macrophages have unique and diverse functions necessary for survival. And, in humans (and other species), they are the most abundant leukocytes in tissues. The Innate functions of macrophages that are best known are their unusual ability to either “Kill” or “Repair”. Since killing is a destructive process and repair is a constructive process, it was stupefying how one cell could exhibit these 2 polar – opposite functions. However, in the late 1980’s, it was shown that macrophages have a unique ability to enzymatically metabolize Arginine to Nitric Oxide (NO, a gaseous non – specific killer molecule) or to Ornithine (a precursor of polyamines and collagen for repair). The dual A...
AHA Scientific Sessions 2019 - Final Program
The American Heart Association’s Scientific Sessions 2019 is bringing big science, big technology, and big networking opportunities to Philadelphia, Pennsylvania this November. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content.
Olives and Olive Oil in Health and Disease Prevention
Olives and Olive Oil in Health and Disease Prevention, Second Edition expands the last releases content and coverage, including new sections on materials in packaging, the Mediterranean diet, metabolic syndrome, diabetic health, generational effects, epigenetics, glycemic control, ketogenic diet, antioxidant effects, the use of olive oil in protection against skin cancer, oleuropein and ERK1/2 MAP-Kinase, oleocanthal and estrogen receptors, and oleocanthal and neurological effects. The book is a valuable resource for food and health researchers, nutritionists, dieticians, pharmacologists, public health scientists, epidemiologists, food technologists, agronomists, analytical chemists, biochemists, biologists, physicians, biotechnologists and students. - Continues the tradition of exploring olives and olive oil from general aspects down to a detailed level of important micro-and micronutrients - Explains how olive oil compares to other oils - Details the many implications for human health and disease, including metabolic health, cardiovascular health and effects on tissue and body systems
Teaching Innovation in University Education: Case Studies and Main Practices
In the last decade, the development of new technologies has made innovation a fundamental pillar of education. Teaching innovation includes the evolution of both teaching and learning models to drive improvements in educational methodologies. Teaching innovation is a pioneer in the understanding and comprehension of the different teaching methodologies and models developed in the academic area. Teaching innovation is a process that seeks validation in the academic and teaching communities at universities in order to promote the improvement and its practices and uses in the future characterized by digital development and data-based methods. Teaching Innovation in University Education: Case St...
The Wind from the East
Internationally celebrated author Almudena Grandes has produced her finest work yet with The Wind from the East, a blend of two narratives set alternately in Madrid and an Andalusian town by the sea. Sara Gómes Morales,given up at birth to be raised by her wealthy godmother,is betrayed on her sixteenth birthday when she is forced to leave her godmother’s home and return to live in poverty with her estranged parents. Tortured by resentment and the loneliness of belonging to neither place,she finds solace as an adult only when she moves to the coastal town. Parallel to Sara’s story is the story of Juan and Damian Olmedo, brothers in love with the same woman. One night an argument incited by jealousy leads Damian to stumble down a flight ofstairs and fall to his death. Suspected ofmurdering his younger brother, Juan flees to the same village that served as Sara’s escape. Deftly engaging, The Wind from the Eastis an epic tale of love and redemption. Almudena Grandes' writing has been compared to the work of classic and contemporary voices such as the Brontë sisters and Isabel Allende.
Resolution Pharmacology - Innovative Therapeutic Approaches Based on the Biology of Resolution to Control Chronic Diseases of Western Societies
In this eBook, we have grouped together 16 original contributions which have addressed the translational potential for therapeutics developed on the conceptual framework of the resolution of inflammation. The take home message of our effort, and the efforts of our colleagues who wrote these pieces, is that completely different drugs can be designed and modelled on the mediators and targets of resolution. By implementing this 180° shift in the way we plan the drug development programme (that is by focusing on agonists and/or promoting the actions of pro-resolution agonists) we can offer a fresh approach to the clinical management of chronic diseases that affect the modern society. With this ...
Self Portrait in Green
'NDiaye is a hypnotic storyteller with an unflinching understanding of the rock-bottom reality of most people's life.' New York Times ' One of France's most exciting prose stylists.' The Guardian. Obsessed by her encounters with the mysterious green women, and haunted by the Garonne River, a nameless narrator seeks them out in La Roele, Paris, Marseille, and Ouagadougou. Each encounter reveals different aspects of the women; real or imagined, dead or alive, seductive or suicidal, driving the narrator deeper into her obsession, in this unsettling exploration of identity, memory and paranoia. Self Portrait in Green is the multi-prize winning, Marie NDiaye's brilliant subversion of the memoir. Written in diary entries, with lyrical prose and dreamlike imagery, we start with and return to the river, which mirrors the narrative by posing more questions than it answers.
El Edificio de la Almudena de Ciudad Universitaria
El paso histórico que supone la apertura de la hiperaula en el Edificio de la Almudena se presenta como una excusa más que pertinente para mirarnos en el espejo del pasado del lugar que habitamos el personal de administración y servicios, los estudiantes, los docentes y los investigadores de la Facultad de Educación de la UCM. De esta excusa nace la exposición «El Edificio de la Almudenade Ciudad Universitaria: La huella del pasado en tiempos de la hiperaula». El documento que a continuación se ofrece pretende ser un complemento a la exposición con una narración más detallada que pueda resultar de interés tanto para quienes tengan la oportunidad de pasear por la exposición, como...
International Arbitration: Law and Practice
International Arbitration: Law and Practice (Third Edition) provides comprehensive and authoritative coverage of the basic principles and legal doctrines, and the practice, of international arbitration. The book contains a systematic, but concise, treatment of all aspects of the arbitral process, including international arbitration agreements, international arbitral proceedings and international arbitral awards. The Third Edition guides both students and practitioners through the entire arbitral process, beginning with drafting, enforcing and interpreting international arbitration agreements, to selecting arbitrators and conducting arbitral proceedings, to recognizing, enforcing and seeking ...
