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Stem Cell-Based Neural Model Systems for Brain Disorders
This detailed volume presents validated and well-adapted procedures involving humanized and/or stem cell-based neural model systems that have proven helpful in better understanding the essential brain functions involved in the pathogenesis of brain disorders. The book explores the generation of multiple neural cell types in 2D and 3D as well as cutting-edge techniques to assay neural function. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Stem Cell-Based Neural Model Systems for Brain Disorders serves as an essential resource for researchers and students in neuroscience, stem cell biology, and related fields.
California Dreaming
California has historically provided a fertile breeding ground for radical modes of architectural thinking, practice and building, which from the 1920s onwards was sparked by the presence of eminent émigré architects. It was also central to the birth of ‘cool’ mid-century Modernism – all in parallel with the intense concentration of design and experimentation in the film, aerospace and tech industries. This AD issue explores the influential formal tropes generated in the nexus between Los Angeles and the Bay Area, as well as the thriving theoretical preoccupations that have brought California's architects global attention. Between Hollywood and the Silicon Valley, this unique context...
Digital And Parametric Architecture
Digital And Parametric Architecture explores the development of the latest digital tools including advance modeling software and computer aided design in the production of architecture. It is a journey through the most fascinating projects, digitally designed and fabricated, during the second decade of the 21st century. The book highlights the use of these technologies to explore tectonic operations such as sectioning, folding, contouring, and tessellating. A wide variety of projects that range in scale and location offer an insight into the architecture of the future.
Fifty Under Fifty
The architects, designers, artists and others represented in Fifty Under Fifty are innovators of our time. After a world-wide search of 50 top architecture and design firms by the editors, lead author Beverly Russell along with Eva Maddox and Farooq Ameen help bring together a unique body of work; all partners in these firms will be 50 years old or under at the time of publication, and represent a forward-thinking generation of creative people, aware of global issues that urgently need solutions through imaginative design. A distinguished five-person jury presided over the final selection: Stanley Tigerman, founding partner, Tigerman McCurry, Chicago; Ralph Johnson, design principal, Perkins...
Raised on Old-Time Country Cooking
Sixteen generations later, the same old winding roads and blazed trails throughout the three novels lead us all back home to nostalgic dishes and the worlds from which they came. Upon arrival at the old home place, we quickly find our favorite room: Mamas kitchen. The familiar sounds of pots and pans and aromas of old-time country cooking float in and out of our senses. Suddenly, visions of chocolate pies swirled high with meringues cooling on the kitchen window sill are as clear as yesterday. The sizzling sounds of Mama frying chicken on the old wood-stove remind us that her kitchen offered southern hospitality at its best. The trip down memory lane of days gone by rekindles the true meaning of Home Sweet Home. As we stop and reminisce, hot tears blur our vision and we ask ourselves where did all the years go?
New Venture Creation
Structured around the idea that innovation is at the core of successful entrepreneurship, this insightful guide by Meyer and Crane establishes innovation as a necessary first step before writing a business plan or developing a financial model. With a focus on pragmatic methods for gaining industry and customer insight and translating this insight into innovative product and service solutions, Meyer and Crane help students design robust business models, financial projections, business plans, and investor presentations. New Venture Creation is devoted to helping students develop compelling business ideas. This is based not only on the authors’ well-known research in product and service innov...
Scooby-Doo Explores Cities
Scooby-Doo and the Mystery Inc. gang are globe-trotting! From Paris to Sydney to New York City, they are doing some big city sight-seeing. The gang explores the landmarks, weather, and geography in each location. Young readers will delight in using the clues in the text and photos to guess which city the gang is visiting before turning the page.
Entrepreneurship
This book shows students how to build successful new enterprises: to conceive, plan, and execute on a new venture idea. Based on research findings, the authors' own experiences and their work with dozens of young entrepreneurial companies, the book shows how innovation is inextricably linked with entrepreneurship. It breaks down all the key steps necessary for success, provides in-depth cases of companies from a variety of industries (with a focus on technology firms), and includes Reader Exercises at the end of each chapter that can be used for team activities.
Paradigms in Computing
Paradigms in Computing: Making, Machines, and Models for Design Agency in Architecture brings together critical, theoretical, and practical research and design that illustrates the plurality of computing approaches within the broad spectrum of design and mediated practices. It is an interrogation of our primary field of architecture through the lens of computing, and yet one that realizes a productive expanding of our métier’s definition and boundaries. It is a compilation that purposefully promotes architecture’s disciplinary reach and incorporations beyond the design and construction of buildings and cities. The book offers a glimpse into the wide range of positions and experiences th...
