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Ketamine
Increasing use of ketamine as a recreational drug in Asia, Europe, and America is a great burden on society at large, leading to aspirational strain, unemployment, and crime. These societal effects have led to growing interest among researchers and clinicians in ketamine’s effects on various systems of the body. Ketamine: Use and Abuse reviews the acute and chronic effects of ketamine on both adult and developing animals and humans. Providing an exhaustive review of the literature, the book is supplemented by the introduction of new data and research. Topics include: The pharmacological properties of ketamine The impact of ketamine on various organ systems, including the central nervous sy...
Ketamine
Describes the history of ketamine, why it became a popular party drug in the twentieth century, how it works, and its side effects.
Ketamine
This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the serious problem of ketamine abuse. The first part of the book focuses on the evidence regarding ketamine abuse, with specific reference to Asian countries, and discusses countermeasures and complication management. It then addresses the mechanisms underlying the antidepressant and side effects of ketamine, which have remained elusive, describing and discussing important new research findings. Further, it explains insights gained from whole brain imaging in rodents and from behavioral pharmacology, and presents evidence regarding the role of gut microbiota, the NMDA receptor GluN2D subunit, and the lateral habenula in the actions of ketamine. These advances form the basis for the safer use of ketamine in patients with treatment-resistant depression and are expected to lead to the development of new antidepressants.
Ketamine
This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the serious problem of ketamine abuse. The first part of the book focuses on the evidence regarding ketamine abuse, with specific reference to Asian countries, and discusses countermeasures and complication management. It then addresses the mechanisms underlying the antidepressant and side effects of ketamine, which have remained elusive, describing and discussing important new research findings. Further, it explains insights gained from whole brain imaging in rodents and from behavioral pharmacology, and presents evidence regarding the role of gut microbiota, the NMDA receptor GluN2D subunit, and the lateral habenula in the actions of ketamine. These advances form the basis for the safer use of ketamine in patients with treatment-resistant depression and are expected to lead to the development of new antidepressants. --
Acute Pain Management
This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.
Hallucinogens
Hallucinogens are drugs that have profound impacts on the users' perceptions of reality. Throughout history, some cultures have embraced hallucinogens as part of a path to spiritual enlightenment. Unfortunately, hallucinogens that are available on the streets can also have terrifying side effects. This book explores the history, effects, and risks of a wide variety of hallucinogenic drugs. From caffeine and aspirin to heroin and meth, drugs are an inescapable part of life in the 21st century. Addiction, once viewed as a shameful secret, is now widely understood to be a brain disease that can be treated. This series explores the many facets of this complex topic, providing students with the f...
Ketamine
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Modern Anesthetics
Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes rather hours. The target effects, such as unconsciousness, are pot- tially life-threatening, as are the side effects of modern anesthetics, such as respi- tory and cardiovascular depression. Finally, the patient’s purposeful responses are not available to guide drug dosage, because, either the patient is unconscious, or more problematically, the patient...
Ketamine Revisited
In the past, ketamine was considered a dangerous medication with the potential for abuse as a recreational drug. Healthcare providers were warned of its dangers and taught to fear its use. With this book, we hope to eliminate any fear and misgivings associated with this drug. It can be a useful medication in many situations, some of which we describe herein. This book discusses the use of ketamine in anesthesia, pain disorders, depression, palliative care, and trauma situations. It also examines ketamine usage in developing countries.
