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The Strangling of Satan
Steve Dalton, an electronics graduate living in a sleepy Cheshire village, had no idea the turn his life would take on a business trip to Malaysia. After pulling off the deal of a lifetime, he finds himself in danger, embroiled in a web of crime and murder that reaches from China to the Middle East and Africa.As he navigates the hazardous terrain of illicit drugs, bogus medicines and vice, Steve needs to figure out if there is anyone he can trust if he is going to uncover the deeper motivations of the criminal syndicate-motivations that may just hit a little close to home in The Strangling of Satan.
The Clinical Neurobiology of Fibromyalgia and Myofascial Pain
Is chronic fatigue syndrome an early process of muscle aging? Is fibromyalgia a central pain state? This book covers the latest developments in pain research as presented at the Fifth World Congress on Myofascial Pain (MYOPAIN 2001). It examines the results of a wide scope of basic and applied research on soft-tissue pain, with a strong focus on therapeutic approaches. Its three main sections explore the neurobiology of central sensitization, regional pain syndromes, and chronic widespread pain. In addition, this well-referenced book presents a fascinating chapter on the complex relationship between muscle pain and aging. Handy graphs, charts, and illustrations make the information easy to a...
Pain and Neurogenic Inflammation
This volume is intended to bring together recent advances in the often separate fields of pain and neurogenic inflammation. To this end, eminent researchers from both domains have contributed in-depth discussion of the mechanisms underlying these processes. Individual chapters focus on important recent discoveries such as the cloning of the capsaicin receptor and the discovery of RAMP proteins for CGRP receptors. This book provides an integrated account of recent advances in the fields of pain and neurogenic inflammation. The volume is intended to bring together studies from eminent researchers in the often separate research fields of pain and inflammation. "Pain and Neurogenic Inflammation" is aimed primarily at postgraduate researchers as well as academic and industrial researchers in pain and inflammation but is also likely to be of interest to undergraduate students seeking a firm grounding in the mechanisms underlying these important clinical conditions.
The Neurobiology of Pain
The last decade has seen major advances in the neurobiology of pain, primarily resulting from a deeper understanding of the way in which pain signals are coded and processed in the nervous system. This volume in the Molecular and Cellular Neurobiology is the first book for many years to present an integrated overview of the current state of research into the neurobiology of chronic and acute pain. While recent molecular aspects of nociception are covered in some detail, the book also emphasises the importance of viewing the pain experience as the co-ordinated response of many different areas of the nervous system. The molecular advances are set in the context of the neurobiological system of...
Encountering Pain
What is persistent pain? How do we communicate pain, not only in words but in visual images and gesture? How do we respond to the pain of another, and can we do it better? Can explaining how pain works help us handle it? This unique compilation of voices addresses these and bigger questions. Defined as having lasted over three months, persistent pain changes the brain and nervous system so pain no longer warns of danger: it seems to be a fault in the system. It is a major cause of disability globally, but it remains difficult to communicate, a problem both to those with pain and those who try to help. Language struggles to bridge the gap, and it raises ethical challenges in its management un...
Translational Pain Research: Comparing preclinical studies and clinical pain management. Lost in translation?
Basic science and clinical pain research is particularly challenging for several reasons. First, pain is a subjective experience in response to nociception that follows actual or potential tissue damage. Since the ability to respond to this warning signal is essential for our survival, the nociceptive system that produces and transmits nociceptive signals is remarkably redundant and involves diffuse regions of the central nervous system. Second, unlike other sensory modalities, pain is a multi-dimensional experience including at least cognitive, affective, and sensory-discriminative components. Third, pain experiences can be influenced by psychological, socioeconomic, cultural, and genetic p...
Marihuana and Medicine
Leading physicians and scientists from around the world critically examine the pharmacological and molecular basis of the therapeutic properties of marihuana and its active ingredient, THC. They detail the broad array of marihuana's effects on brain function, the immune system, male and female reproductive functions, and cardiac and pulmonary functions, as well as evaluate its clinical applications in psychiatry, glaucoma, pain management, cancer chemotherapy, and AIDS treatment. Their studies indicate that marihuana persistently impairs the brain and reproductive function, and that marihuana smoke is more toxic and damaging to the lung than tobacco smoke. Marihuana and Medicine's reports of the latest findings on the pharmacological and molecular mechanisms of marihuana and of its clinical manifestations will be essential reading for physicians, psychiatrists, pharmacologists, health-care professionals, policy makers, public health officials, and attorneys.
Psychoneural Reduction
John Bickle presents a new type of reductionism, one that is stronger than one-way dependency yet sidesteps the arguments that sank classical reductionism.
Pain Management E-Book
Regarded as the premiere clinical reference in its field, Pain Management, 2nd Edition, edited by noted pain authority Dr. Steven Waldman, provides comprehensive, practical, highly visual guidance to help you effectively apply the most recent evidence-based advances in pain management. This popular text has been updated with 13 new chapters that include the latest information on interventional and ultrasound-guided techniques, acute regional pain nerve blocks, and more. A user-friendly format with lavish illustrations enables you to access trusted guidance quickly...and apply the information easily...to bring effective pain relief to your patients. Tap into the experience of the book’s edi...
Synaptic Plasticity in Pain
Primary sensory neurons respond to peripheral stimulation and project to the spinal cord. Specifically, the population of neurons which respond to damaging stimuli terminate in the superficial layers of the dorsal horn. Therefore, the dorsal horns constitute the first relay site for nociceptive fibre terminals which make synaptic contacts with second order neurons. It has recently become clear that the strength of this first pain synapse is plastic and modifiable by several modulators, including neuronal and non-neuronal regulators, and studies on the fundamental processes regulating the plasticity of the first pain synapse have resulted in the identification of new targets for the treatment of chronic pain. This book will be of interest to a wide readership in the pain field.
