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This book provides information on the aortic valve. Written in a comprehensive style, it emphasizes the principles behind the development of artificial valves. It covers the principles of valve geometry, tissue structure and function relationships, valve dynamics, fluid dynamics, mechanical stresses, echocardiographic images, mechanisms of valve sounds, valvular pathology, and design and performance of bioprosthetic valves. It enhances our understanding of angiographic and echocardiographic images and calcific stenosis, and will be of value in the development of better prostheses. The Aortic Valve is the ideal text for biomedical engineers and a unique resource for teaching interdisciplinary approaches to medical and engineering students. This work is also an indispensible source for cardiac surgeons, pathologists, cardiologists, and manufacturers of prosthetic valves.
Written and edited by an outstanding team of experts in the field, Transcatheter Aortic Valve Implantation offers a multidisciplinary approach to this rapidly expanding procedure. Recent studies have shown transcatheter aortic valve implantation (TAVI) to be as effective as surgical aortic valve repair (SAVR), with demonstrably better outcomes for low, intermediate, and high-risk patients. Under the editorial leadership of Drs. Catherine M. Otto, Bernard D. Prendergast, and Simon Redwood, this practical reference incorporates recent research on patient selection, discusses current guidelines, and covers the new devices developed to address this fast-growing area. - Follows the patient journe...
Currently, aortic stenosis is the most frequent heart valve disease in developed countries and its prevalence increases with the aging of the population. Affecting 3-5 percent of persons older than 65 years of age, it makes a large personal and economical impact. The increasing number of elderly patients with aortic stenosis brings advances in all medical specialties dealing with this clinical entity. Patients previously considered too old or ill are now indicated for aortic valve replacement procedures. This book tries to cover current issues of aortic valve stenosis management with stress on new trends in diagnostics and treatment.
This issue of Cardiology Clinics, guest edited by Drs. Marie-Annick Clavel and Philippe Pibarot, focuses on Aortic Valve Disease. Articles in this issue include, but are not limited to: Pathophysiology of Aortic Stenosis and future perspectives for medical therapy, Assessment of Aortic Stenosis Severity, Assessment of Cardiac Damage in Aortic stenosis, Aortic Stenosis with Other Concomitant Valvular Disease (AR, MR, TR), Biomarker in Aortic Stenosis, Aortic stenosis guidelines: evidence gaps and changing concepts, Heart Valve Clinics and Heart Valve Centers, Frailty and Multi-Comorbidities in Aortic Stenosis, Procedures and Outcomes of Surgical Aortic Valve Replacement, Patient selection and Work-up for Transcatheter Aortic Valve Replacement, Procedures and Outcomes of Transcatheter Aortic Valve Replacement, Sex differences in the Pathophysiology, Diagnosis, and Management of Aortic Stenosis, Implications of Aortic stenosis in Pregnancy and Non-Cardiac Surgery.
This book provides comprehensive information on transcatheter aortic valve implantation (TAVI), which was introduced for the treatment of aortic valve disease less than two decades ago. It explains how TAVI has delivered satisfactory results even in high and intermediate risk patients and outlines how it continues to evolve, thus requiring awareness of state of the art approaches to indication, risk stratification, device choice, procedure, and follow-up. In addition, it reports on the complex and multidisciplinary approach needed to maximize the efficacy, safety, and appropriateness of TAVI, providing detailed clinical, interventional and surgical perspectives focusing on the development of this cardiovascular intervention. Starting with the history of TAVI, addressing the interventional anatomy of aortic valve disease, and reporting on the expert authors’ day-to-day experiences, this highly informative book offers an essential update for all cardiologists and surgeons interested in transcatheter aortic valve implantation, as well as any clinician, decision-maker and stakeholder involved in patient selection, procedural management, and follow-up.
This book will explore the many aspects of the transcatheter aortic valve replacement, from the clinical data supporting the observed worldwide diffusion, to the technicalities that evolved over time in parallel with the continuous new iterations of available devices. Both the interventionalists looking for a reference to literature milestones and the interventionalists searching for the description and execution of the procedure will find what they are looking for. Many answers will be there through the pages, but also some pending questions to fuel future developments and to further refine a procedure that truly changed the landscape of cardiology.
Calcific aortic valve stenosis is the most frequent valvular heart disease in Western countries, affecting up to 13% of individuals over 75 years. The disease is associated with considerable morbidity and mortality. It is characterized by fibro-calcification of aortic valve cusps and concomitant left ventricular remodelling due to chronic pressure overload, which can evolve into overt heart failure. It progresses very slowly until the onset of symptoms, the indication for aortic valve replacement. Today, about 300,000 aortic valve replacements are performed annually worldwide, either via surgery or transcatheter implantation. This is the only treatment shown to improve survival. There is no ...
Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.
This concise manual describes in detail how to perform a transcatheter aortic valve replacement (TAVR) procedure and provides cardiac surgeons and cardiologists with the foundation necessary to begin practicing TAVR. It includes background on the landmark data establishing the field of TAVR, instructions in the pre- and post-operative management of TAVR patients, and technical descriptions of the newest and most common devices and how to use them. Written by leaders in the field, it offers an unbiased, academic review and describes the experience of colleagues who have learned through trial and error. The Transcatheter Aortic Valve Replacement Manual is an essential resource for physicians and related professionals, residents, fellows, and graduate students in cardiology, cardiac surgery, thoracic surgery, and vascular surgery