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Our understanding of biological communication has grown significantly during the past decade. The advances in knowledge about the chemical nature of signals and their corresponding reception by specialized cells have led to identification, characterization, purification, cloning, and expression of specific receptor molecules. While the earlier literature emphasized com partmentalized treatment of informational molecules and their interaction with receptors, the progress in the recent past has allowed cross-fertilization in the examination of the of actions and mechanisms of steroid and protein hormones and other messengers. Investigators now have an increased ap preciation of the multiple ef...
Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Collection of short stories by Ari Sitaramayya
As the title indicates, this book is a critical study of an Indian epic, ëThe Ramayanaí. It proceeds in the same order as that of Sanskrit original consisting of : Bala kanda, Ayodhya kanda, Aranya kanda, Kishkindha kanda, Sundara kanda, Yuddha kanda and Uttara kanda. While Valmikiís Ramayana is composed of about 24,000 slokas (verses), ëRamayana the Poisonous Treeí consists of 16 stories, long and short, accompanied by 11 ëlinksí (narratives that ëlinkí the stories) and 504 foot-notes that show evidence from the Sanskrit original in support of the critique. Besides the main components of the text, this book has a long ëPrefaceí discussing the social essence of the epic in the con...
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Stories based on social themes.
This volume foxuses on the status of Ca2+ ions in regulation of phototransduction, light adaptation and the recovery phase in vertebrate photoreceptors. Particular emphasis is given to Ca2+-binding proteins and their targets, among them particulate guanylate cyclases, GPCR-coupled kinases and cyclic nucleotide-gated cation channels. The book also expands our understanding of events invovling Ca2+ in the retinal pigment epithelium, in synaptic transmission and secondary retinal neurons. A significant part of the book is dedicated to the role of Ca2+ in invertebrate phototransduction, the best-studied phospholipid-mediated signal transduction pathway. Several chapters explore association of gene defects with human retina disease and the generation of animal models of retinal degeneration.