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An in-depth look at genetic alteration in the natural world and the oppositions to it, seen through the case study of a gene drive for malaria. May We Make the World? is an engaging reflection on the history, nature, goal, and meaning of using a new technological idea—CRISPR-based genetic engineering—to alter the genome of the mosquito that carries malaria. This technology, called a “gene drive,” can alter the sex ratio in Anopheles gambiae mosquitoes, the key vector for falciparum, the deadliest form of malaria. P. Falciparum kills 400,000 people a year, largely the poorest children in the world among them. In her sobering examination of the issue, Laurie Zoloth considers the leadin...
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