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Vitamins and Hormones
Vitamins and Hormones
Drug Design
Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design of organophosphate and carbamate inhibitors of cholinesterases. The text also describes the design of reactivators for irreversibly blocked acetylcholinesterase; drug design based on the inhibition of protein synthesis in the context of susceptible enzymic reactions; as well as the role of enzymes and their synthesis as a target for antibiotic action. The rational design of antiviral agents; the design of penicillin; the design of peptide hormone analogs; as well as the advances in the design of diuretics are also considered. The book further tackles the design of biologically active steroids; the rational elements in the development of superior neuromuscular blocking agents; and the design of tumor-inhibitory alkylating drugs. Pharmacologists, chemists, and people involved in drug design will find the book invaluable.
The Pituitary Gland, Volume 3
This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1966. This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived
Pediatric Anesthesia
No longer merely a subspecialty, pediatric anesthesia is now a professional entity in its own right, as is amply demonstrated in this comprehensive addition to the medical and surgical literature. Pediatric Anesthesia: Basic Principles-State of the Art-Future comprises the contributions of 150 experts in the field from all over the world, providing this book with a truly global perspective. This textbook will help anesthesiologists already interested in pediatric anesthesia to the knowledge and skills inherent to the safe practice of anesthesia for infants and children.
The Peptides
The Peptides, Volume II: Synthesis, Occurrence, and Action of Biologically Active Polypeptides focuses on the synthesis of biologically active polypeptides and analogues. The publication first offers information on linear peptides and heterodetic cyclic peptides. Discussions focus on depsipeptides, polycyclic and monocyclic disulfides, naturally occurring biologically active peptides, glandular hormones, and tissue hormones. The text then ponders on homodetic cyclic peptides, including homodetic cyclic homomeric peptide antibiotics, polycyclic biologically active polypeptides, and homodetic cyclic heteromeric peptide antibiotics. The manuscript takes a look at the problems related with the synthesis of biologically active polypeptides, giving emphasis to a number of movements which elaborated on the matter and the advancements of preparative techniques and approaches leading to the purification of intermediates and end products. The publication is a valuable reference for researchers interested in the occurrence, synthesis, and action of biologically active polypeptides.
Pharmacology of Hormonal Polypeptides and Proteins
It can be concluded (under the specific experimental procedures em ployed) that:- 1) HCG labelled with 1 - 2 atoms of radioactive iodine did not differ sig nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is not concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intravenous injection; 6) There are four different phases of ovarian uptake of HCG, namely: the ...
Clinical Endocrinology
Periodically in the evolution of an important branch of clinical medicine there develops a critical need for a textbook which combines with the clinical aspects of disease syndromes an in-depth review of the sciences basic to the disorders discussed, as well as a carefully selected but com prehensive review of pertinent literature. LABHART'S Clinical Endo crinology revised and translated into English provides for this need in the field of endocrinology in an exemplary manner. Prof. LABHART has selected his individual authors with great care, and they in turn have provided authoritative monographs. An interesting, useful and informative introduction to each chapter is provided by a tabulation...
The Pituitary Gland
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Ergot Alkaloids and Related Compounds
With contribution by numerous experts
