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Internationally renowned specialists present a comprehensive survey of the latest advances in this area. The biosynthetic and structural relationships of these compounds are summarized and newly discovered alkaloids described. Discusses versatile biomimetic procedures as well as the pharmacology and clinical applications of monoterpenoid indole alkaloids. Botanical names of all plants cited have been extensively referenced.
Thoroughly revised and extensively expanded, this encyclopedic, highly acclaimed title addresses all aspects of the etiology, pathogenesis, diagnosis, initial treatment and long-term management of all varieties of thyroid cancer. Expertly edited by Drs. Leonard Wartofsky and Douglas Van Nostrand, this gold standard reference is divided into 11 Parts: General Considerations on Thyroid Cancer; General Considerations on Nuclear Medicine; the Thyroid Nodule; Well-Differentiated Thyroid Cancer; Variants of Thyroid Cancer, Undifferentiated Tumors: Medullary Thyroid Carcinoma; Undifferentiated Tumors: Thyroid Lymphoma; Undifferentiated Tumors: Anaplastic Thyroid Cancer; New Frontiers and Future Dir...
The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case. Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident.
Focuses on fundamental aspects of nano-electro-optics. Starting with fiber probes and related devices for generating and detecting the optical near-field with high efficiency and resolution, the next chapter addresses the modulation of an electron beam by optical near-fields. Further topics include: fluorescence spectroscopy, in which sample molecules are excited by the evanescent surface plasmon field close to metallic surfaces; spatially resolved near-field photoluminescence spectroscopy of semiconductor quantum dots, which will become an essential issue in future electro-optical devices and systems; and, finally, the quantum theory of the optical near-field. This latter theory accounts for all the essential features of the interaction between optical near-fields and nanomaterials, atoms and molecules.
The book reviews and reports the recent progress and knowledge on the specific impact of current and projected urban overheating as well as of the urban mitigation technologies on mortality and morbidity and urban vulnerability. It presents recent data and developments on the topic reported by some of the more distinguished researchers in this area. In parallel, it discusses new findings related to the characteristics and the magnitude of urban overheating and reports and analyzes the recent knowledge on the synergies between urban heat island and heatwaves. This book helps to advance our understanding on the interaction between Urban Heat Island (UHI) and overheating as well as their impact on energy demand and public health globally. Exploring the interaction between UHI and energy consumption requires the understanding on the dynamics of UHI intensity and air pollution index in different land use and how such interactions may vary in different cities in the world. Moreover, this book focuses on different cities in Australia, Austria, Belgium, Brazil, Canada, Cyprus, Greece, Hong Kong, India, Asia, Spain, UK, and USA.
In this concise, gold-standard 4th edition book, the volume editors and authors synthesize the prior three editions and provide a comprehensive and expanded review on the latest in the diagnosis and management of thyroid nodules, as well as an update on parathyroid disease and non-endocrine lesions of the neck. This user-friendly edition again emphasizes a multidisciplinary approach to thyroid ultrasound and UGFNA, offering all the new information and subtleties clinicians must know in the application of this technique, now firmly established as a primary tool for diagnosing and managing thyroid disease. Developed by renowned experts in thyroid and parathyroid disease, the book covers not on...
Modern Methods of Plant Analysis When the handbook Modern Methods ofPlant Analysis, was first introduced in 1954, the considerations were: 1. the dependence of scientific progress in biologyon the improvement of existing and the introduction of new methods; 2. the difficulty in finding many new analytical methods in specialized journals which are normally not accessible to experimental plant biologists; 3. the fact that in the methods sections of papers the description of methods is frequently so compact, or even sometimes so incomplete, that it is difficult to reproduce experiments. These considerations still stand today. The series was highly successful, seven volumes appearing between 195...