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Overcoming challenges in microbial immunology: 2022
At Frontiers our mission is to make science open – so that scientists can collaborate better and innovate faster to deliver the solutions that enable healthy lives on a healthy planet. We do this through our community driven Open Access journals. As researchers across the globe work on tackling the challenges facing immunology in the field of Microbial Immunology, they publish their success stories. However, it is equally important for researchers to discuss the challenges they face on the road to success, as most innovation begins with failure. Our Open Access publication allows researchers to discover the areas for development in the field and to provide a focus for future research. This Research Topic will highlight the importance of learning from one another in the scientific community and continue to highlight areas for progress. This Research Topic welcomes Reviews, Mini-reviews, Original Research, and Perspectives that highlight the field of Microbial Immunology from the following perspectives: - Recent success stories with a focus on the challenges faced and overcame. - Current challenges in the field and emerging research to innovate.
Autoimmuno-Anti-Tumour Immunity (AATI) – Understanding the Immune Responses against “Self” & “Altered-self”
The brief description of tumours being “wounds that do not heal” by Dr Harold F. Dworak nearly three decades ago (N Engl J Med 1986) has provided not only a vivid illustration of neoplastic diseases in general but also, in retrospect conceptually, a plausible immunological definition of cancers. Based on our current understanding in the field, it could have even a multi-dimensional meaning attached with. This relates to several important issues which need to be addressed further, i.e. in terms of a close link between chronic inflammation and tumourigenesis widely observed; clinical and experimental evidence of immunity against tumours versus the highly immunosuppressive tumour microenvir...
