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Covers a widespread view of Quality by Design (QbD) encompassing the many stages involved in the development of a new drug product. The book provides a broad view of Quality by Design (QbD) and shows how QbD concepts and analysis facilitate the development and manufacture of high quality products. QbD is seen as a framework for building process understanding, for implementing robust and effective manufacturing processes and provides the underpinnings for a science-based regulation of the pharmaceutical industry. Edited by the three renowned researchers in the field, Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture guides pharmaceutical engineers and scie...
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A primer on modeling concepts and applications that is specifically geared toward the environmental field. Sections on modeling terminology, the uses of models, the model-building process, and the interpretation of output provide the foundation for detailed applications. After an introduction to the basics of dynamic modeling, the book leads students through an analysis of several environmental problems, including surface-water pollution, matter-cycling disruptions, and global warming. The scientific and technical context is provided for each problem, and the methods for analyzing and designing appropriate modeling approaches is provided. While the mathematical content does not exceed the level of a first-semester calculus course, the book gives students all of the background, examples, and practice exercises needed both to use and understand environmental modeling. It is suitable for upper-level undergraduate and beginning-graduate level environmental professionals seeking an introduction to modeling in their field.
The 2nd edition provides an update of information since the publication of the first edition including best practices for managing process safety developed by industry as well as incorporate the additional process safety elements. In addition the book includes a focus on maintaining and improving a Process Safety Management (PSM) System. This 2nd edition also provides "how to information to" determine process safety performance status, implement one or more new elements into an existing PSM system, maintain or improve an existing PSM system, and manage future process safety performance.
An insight into the ministry of priests who over the centuries and across the world have voluntarily provided Catholic service personnel with the solace of religion far away from home and frequently in danger.