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andererseits - Yearbook of Transatlantic German Studies
andererseits provides a forum for research, commentary, and creative work on topics related to the German-speaking world and the field of German Studies. Works presented in the publication come from a wide variety of genres including book reviews, poetry, essays, editorials, forum discussions, academic notes, lectures, and traditional peer-reviewed academic articles. In addition, we welcome contributions by journalists, librarians, archivists, and other commentators interested in German Studies broadly conceived. As a specifically transatlantic endeavor, we also highlight select topics in American Studies that impact German Studies. By publishing such a diverse array of material, we hope to demonstrate the extraordinary value of the humanities in general, and German Studies in particular, on a variety of intellectual and cultural levels. This issue features sections about German Studies approaches to media literacy, Stephen Dowden's book »Modernism and Mimesis« and the poetics of ambiguous memory.
Biomolecular Simulations in Structure-Based Drug Discovery
A guide to applying the power of modern simulation tools to better drug design Biomolecular Simulations in Structure-based Drug Discovery offers an up-to-date and comprehensive review of modern simulation tools and their applications in real-life drug discovery, for better and quicker results in structure-based drug design. The authors describe common tools used in the biomolecular simulation of drugs and their targets and offer an analysis of the accuracy of the predictions. They also show how to integrate modeling with other experimental data. Filled with numerous case studies from different therapeutic fields, the book helps professionals to quickly adopt these new methods for their curre...
Nanobody
Nanobodies have become outstanding tools for biomedical research, diagnostics and therapy. Recent advances in the identification and functionalization of target-specific nanobodies now make nanobody-based approaches broadly available to many researches in the field. This book provides a compilation of original research articles and comprehensive reviews covering important and up to date aspects of research on nanobodies and their applications for immunoassays, proteomics, protein crystallization and in vitro and in vivo imaging.
Reflections on the Universal Declaration of Human Rights
The Right to Seek Asylum.
Single-Domain Antibodies: Biology, Engineering and Emerging Applications
Single-domain antibodies (sdAbs) represent the minimal antigen binding-competent form of the immunoglobulin domain and have unique properties and applications. SdAbs are naturally produced as the variable domains of the heavy chain-only antibodies of camelid ruminants and cartilaginous fishes, but can also be engineered synthetically from autonomous human or mouse VH or VL domains. The scope of this research topic and associated e-book covers current understanding and new developments in (i) the biology, immunology and immunogenetics of sdAbs in camelids and cartilaginous fishes, (ii) strategies for sdAb discovery, (iii) protein engineering approaches to increase the solubility, stability and antigen-binding affinity of sdAbs and (iv) specialized applications of sdAbs in areas such diagnostics, imaging and therapeutics.
Animal Cell Technology Meets Genomics
The 18th ESACT meeting was celebrated in Granada (Spain) in May 2003, and was entitled "Animal Cell Technology Meets Genomics", in order to reflect that the emerging technologies in the area of genomics, proteomics and other "-omics"-type disciplines will provide key technological assets to increase knowledge and open new horizons in animal cell technology. During the meeting a variety of top-class emerging technologies were presented together with the lastest advances in more mature industrial areas. The meeting was opened by a first session devoted to the understanding of basic cellular mechanisms, and four sessions focused on applied aspects of animal cell technology: Cell-based therapies and gene-based therapies, target discovery and biopharmaceuticals. The Granada Meeting has also seen a special focus on forefront industrial case studies. The spirit and scientific excellence of the 18th ESACT meeting is now reflected in different chapters of the book. The book presents, in form of short papers, a high number of the contributions to the meeting, and has been prepared with the aim to provide a relevant reference of the current research efforts in Animal Cell Technology.
Recombinant Gene Expression
Since newly created beings are often perceived as either wholly good or bad, the genetic alteration of living cells impacts directly on a symbolic meaning deeply imbedded in every culture. During the earlier years of gene expression research, te- nological applications were confined mainly to academic and industrial laboratories, and were perceived as highly beneficial since molecules that were previously unable to be separated or synthesized became accessible as therapeutic agents. Such were the success stories of hormones, antibodies, and vaccines produced in the bacterium Escherichia coli. Originally this bacterium gained fame among humans for being an unwanted host in the intestine, or w...
Best White Wine on Earth
A celebrated wine journalist presents a comprehensive, entertaining primer on one of the most beloved wines of our time: Riesling. Diverse, drinkable, aromatic, and refreshing, Riesling is a chameleon among white wines. From its food-friendly flavor and favorable price point to its ability to be either bone-dry or honey-sweet, there are very good reasons to argue that Riesling is not just a popular wine of the moment, but the finest white of our time. In Best White Wine on Earth, wine journalist and Riesling enthusiast Stuart Pigott extols the virtues of his favorite varietal and explores the history behind this magnificent grape. Traveling to the great Riesling-producing regions of the world—from North America to Europe, Australia, New Zealand, and South America—Pigott provides tasting notes, top-rated recommendations, and fascinating insights into how the wine is made, all while making an impassioned case that it is, truly, the best white on earth. Written simply enough for a novice, but with enough expertise and insight to satisfy the most sophisticated collector, this is a must-have guide for any white wine enthusiast.
Empresses and Queens in the Courtly Public Sphere from the 17th to the 20th Century
Eight case studies focus on a specific group of European Empress consorts and Queen regnants from the 17th to the 20th century and their relationship to the media, using a unique, comparative, cross-media, and cross-period approach.
