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From Biosynthesis to Total Synthesis
Focusing on biosynthesis, this book provides readers with approaches and methodologies for modern organic synthesis. By discussing major biosynthetic pathways and their chemical reactions, transformations, and natural products applications; it links biosynthetic mechanisms and more efficient total synthesis. • Describes four major biosynthetic pathways (acetate, mevalonate, shikimic acid, and mixed pathways and alkaloids) and their related mechanisms • Covers reactions, tactics, and strategies for chemical transformations, linking biosynthetic processes and total synthesis • Includes strategies for optimal synthetic plans and introduces a modern molecular approach to natural product synthesis and applications • Acts as a key reference for industry and academic readers looking to advance knowledge in classical total synthesis, organic synthesis, and future directions in the field
Art in Biosynthesis
Art in Biosynthesis: The Synthetic Chemists Challenge, Volume 1 presents representative examples whose biosynthetic pathways are known on the basis of experimentation. This book is divided into 44 chapters that demonstrate the creativity associated with the construction of molecular frameworks. It is a work of appreciation and criticism of the complexity of biosynthetic processes and of the interaction between man, the organic chemist, and Nature. This text describes an established biosynthetic sequence which is a challenge to the synthetic organic chemist to imitate and to equal Nature. The aim of each chapter is to enable a quick comparison of the specific synthetic strategies. This work covers the biosynthesis of natural antibiotics, amino acids, enzymes, fatty acids, and vitamins. This book will prove useful to organic chemists and researchers.
Biosynthesis
Concerned with discovering the chemical pathways of biosynthesis, this book devotes four chapters to the use of isotopes in biosynthetic research and the biosynthesis of enzyme cofactors and vitamin B12 and of reduced polyketides such as erythromycin. The topics covered demonstrate the revolution that has occurred in biosynthetic studies with the advent of gene cloning and overexpression. Yet the book also shows that the more classical approach to biosynthetic studies must go hand in hand with these new techniques.
Amino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering
This book presents the current knowledge of fundamental as well as applied microbiology of amino acids. Coverage details the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The book also examines the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and as food and feed additives.
Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery (2)
This second edition integrates many new findings into the underlying enzymatic mechanisms and the catalytic machinery for building the varied and complex end product metabolites. This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists.
Food Biosynthesis
Food Biosynthesis, Volume One in the Handbook of Food Bioengineering series, describes the main aspects related to the biological production of synthetic ingredients and natural foods, highlighting the impact of bacteria and plants in the biosynthesis of key food components. Biosynthesis methods could help solve issues like food shortages, providing consumers with preferred 'natural' food options. This book represents how biologically synthesized ingredients, such as vanilla flavoring, soy, milk and egg substitutes can be utilized as a desired option future foods. It is ideal for scientists and researchers who want to improve their knowledge on the field of food biosynthesis. - Presents practical approaches of biosynthesis and the impact of biological origin on the field of food engineering - Offers alternative applications to produce natural foods - Includes processes and techniques to produce health promoting foods - Discusses the positive effects of biosynthesis on microbial production to enhance food safety - Offers a variety of perspectives on biosynthesis and its benefits for food ingredient production
Green Biosynthesis of Nanoparticles
There are physical and chemical methods of synthesis of nanomaterials. But due to the damage caused by these methods to the environment there is a pressing need of green nanotechnology, which is a clean and eco-friendly technology for the development of nanomaterials. The present book includes green synthesis of nanoparticles by algae, diatoms and plants. The mechanism behind the synthesis of nanoparticles will also be discussed. The book would be a valuable resource for students, researchers and teachers of biology, chemistry, chemical technology, nanotechnology, microbial technology and those who are interested in green nanotechnology.
The Biosynthesis of Secondary Metabolites
This is a book about experiments and results of experiments. The results described are the fruit of thirty years' labour in the field of secondary metabolism. Secondary metabolism, more than any other part of the chemistry of life, has been the special preserve of organic chemists. Investiga tion of secondary metabolism began with curiosity about the struc tures of compounds isolated from natural sources, i.e. secondary metabolites. Coeval with structure determination there has been a curiosity about the origins and mechanism of formation of secondary metabolites (or natural products as they have been called). It is the experimental outcome of this curiosity that is described here. This acco...
The Biosynthesis of Secondary Metabolites
The chief purpose of such new editions is to bring the text up to date. This I have tried to do. The danger with such endeavours is that the book becomes corpulent. This I have tried to avoid. In so doing I am evermore conscious of how much material has had to be omitted. As before the references (ca. 770 of them) which are cited are intended in part to provide the reader with access to material that has been omitted. I am deeply grateful to Mrs Marjorie Romanowicz for preparing the typed manuscript for this edition with customary accuracy and efficiency, to my wife Margaret for checking the references, and to research students Karl Cable, Lucy Hyatt, Mashupye Kgaphola and Andrew Knaggs for ...
Biosynthesis
Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The A...
