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During the past decade there has been an enormous increase in knowledge of multiple myeloma and related disorders, reflected in the publication of more than 5000 articles on the subject in scientific journals. Much of this has come about as new technologies have made it possible to refine studies on chromosomes and genes and to gain information abo
Multiple myeloma has been one of the most studied malignancies since its discovery in the mid-nineteenth century. During the last decade, knowledge about the disease has advanced rapidly. 'Multiple Myeloma' provides a comprehensive and authoritative account of the condition emphasising current diagnosis and management. The book examines the impact that sophisticated new techniques (such as immunophenotyping, cell sorting, cytogenetics, growth-factor analysis, and molecular biology) have had on our understanding of the disease. New treatment methods have not been introduced without difficulties, and the risk factors of intensive antibacterial and antiviral therapies and transplantation are fully discussed. The contributors are all recognised experts in the field with 'hands on' experience, making this invaluable reading for oncologists and haematologists.
From a process that from the days of Vir chow and Rokitansky, primarily stimulated the relatively narrow interest of pathologists, amyloidosis has risen full-blown as one of the most important of disease complexes. Its presence dominat:es the lesions of Alzheimer's disease, a disease affecting an estimated 2. 5 million people in the U. S. A. and thereby closely rivaling stroke as the third most common cause of death. If, as it has been de scribed, Alzheimer's disease is the "Disease of the Century," then amy loidosis is the Disease Complex of the Ages. It affects in one or more of its manifestations every organ of the body, and is at least as old as the afflicted Egyptian mummies of the pyra...
Abstracts contains the abstracts of work presented at the 7th International Congress of Pharmacology: invited lectures, symposia, methodological seminars, and free communications. The abstracts are organized in chronological order of presentation at the Congress. Some abstracts focus on chemistry and biochemistry of pituitary endorphins and their precursors; the biosynthesis and release of the enkephalins; enkephalin dynamics and neuronal localization; and physiological and pathophysiological relevance of the opiate receptors and their endogenous ligands. Other papers center on the mechanism of muscarinic receptor action; regulation of cholinergic receptor metabolism in skeletal muscle; the role of vitamin E in ozone-induced pulmonary toxicity; alcohol and electrophysiology of the central nervous system; and pharmacokinetic aspects of drug-alcohol interaction.
First multi-year cumulation covers six years: 1965-70.