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RNA Metabolism and Gene Expression in Archaea
This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications of gene expression, it presents the current state of knowledge on archaeal RNA biology in 13 chapters. Topics covered include the modification and maturation of RNAs, the function of small non-coding RNAs and the CRISPR-Cas defense system. While Archaea have long been considered exotic microbial extremophiles, they are now increasingly being recognized as important model microorganisms for the study of molecular mechanisms conserved across the three domains of life, and with regard to the relevance of similarities and differences to eukaryotes and bacteria. This unique book offers a valuable resource for all readers interested in the regulation of gene expression in Archaea and RNA metabolism in general.
Non-Coding RNAs
General inspection of a role performed in the cell by RNAs allows us to distinguish three major groups of transcripts: I. protein-coding mRNAs, II. non-coding housekeeping and III. regulatory RNAs. The housekeeping RNAs include RNA classes that are generally, constitutively expressed and whose presence is required for normal function and viability of the cells. On the other hand, a group of regulatory RNAs includes RNA species that are expressed at certain stages of organism development or cell differentiation or as a response to external stimuli and can affect expression of other genes on the levels of transcription or translation. Non-coding RNA transcripts form a heterogeneous class of RN...
Ribonucleases
Ribonucleases are a ubiquitous and functionally diverse group of enzymes that have a common ability to cleave RNA. Either through scission of internal phosphodiesters, or removal of nucleotides from RNA 5’ or 3’ ends, ribonucleases perform essential roles in gene expression and regulation, genome replication and maintenance, host defense, stress response, and viral strategies of infection. Ribonucleases have also served as highly informative models to understand virtually every aspect of biomolecular structure and function. The fifteen chapters in this volume are written by recognized researchers in the field, and provide in-depth analyses of the major ribonuclease families. Particular f...
Evolutionary Tinkering in Gene Expression
The Workshop on "Evolutionary Tinkering in Gene Expression" which was held at the end of August 1988. was planned to celebrate 20 successful Advanced Study Institutes (A. S. I.) in Molecular and Cell Biology. The first Institute was held in 1966 on the Island of Spetsai. after a N. A. T. O. suggestion and was entirely financed by N. A. T. O. The success was immediately so great that the Institute grew very rapidly and in the following years. N. A. T. O .• E. M. B. O. (since 1972) and F. E. B. S. (since 1981) co-sponsored it. Since the start of the AS!. the U. S. National Science Foundation has granted travel money for a limited number of American participants each year. In addition. the course was supported by minor industrial subsidies of varying amounts which enabled the organizers to improve some of the local facilities particularly with respect to the lecture hall. In particular. Boehringer Mannheim has contributed since 1966. Furthermore. the Greek Ministry of Science and Culture has provided support at least for a social event during each ASI.
Les archées, micro-organismes du troisième domaine du vivant 2
Les archées (ou Archaea) constituent un nouveau domaine du vivant au côté des bactéries et des eucaryotes. Ces micro-organismes sont uniques par leurs aspects cellulaires et moléculaires. Ils possèdent des liens évolutifs avec les premières cellules eucaryotes et sont désormais utilisés pour élucider des questions biologiques fondamentales. Championnes de l’extrêmophilie, les archées permettent de lever le voile sur les limites du vivant sur Terre. Les archées, micro-organismes du troisième domaine du vivant 2 expose les divers mécanismes moléculaires impliqués dans les processus fondamentaux du maintien des génomes et de la régulation de l’expression génique des cel...
Les archées, micro-organismes du troisième domaine du vivant 1
Les archées (ou Archaea) constituent un nouveau domaine du vivant au côté des bactéries et des eucaryotes. Ces micro-organismes sont uniques par leurs aspects cellulaires et moléculaires. Ils possèdent des liens évolutifs avec les premières cellules eucaryotes et sont désormais utilisés pour élucider des questions biologiques fondamentales. Championnes de l’extrêmophilie, les archées permettent de lever le voile sur les limites du vivant sur Terre. Les archées, micro-organismes du troisième domaine du vivant 1 présente la découverte et l’évolution du champ de recherche des archées. Il s’interroge sur leur histoire évolutive, leur intégration dans l’arbre du vivant et examine ce monde complexe et extrêmement diversifié au vu de leurs niches écologiques et de leur virosphère encore largement inexplorée.
Pacific Symposium on Biocomputing 2002
The Pacific Symposium on Biocomputing brings together key researchers from the international biocomputing community. It is designed to be maximally responsive to the need for critical mass in subdisciplines within biocomputing. This book contains peer-reviewed articles in computational biology.
Biocomputing 2002 - Proceedings Of The Pacific Symposium
The Pacific Symposium on Biocomputing brings together key researchers from the international biocomputing community. It is designed to be maximally responsive to the need for critical mass in subdisciplines within biocomputing. This book contains peer-reviewed articles in computational biology.
