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A Breath Before Dying
After 30 years of failed relationships and poor choices, a self-declared loser searches for the strength to end his life, but fate shows him that the future can be quite different from the past.
A Breath Before Dying
After 30 years of failed relationships and poor choices, a self-declared loser searches for the strength to end his life, but fate shows him that the future can be quite different from the past.
American Vampire
This is my life, my reality. I am not a vampire, not a real one anyway. I am simply the lucky lottery winner of an all-star line-up of illness. From Anemia to Xeroderma Pigmentosum and all points between. The real diseases which have helped created the Vampire myth. Yes, I drink blood and my skin burns in sunlight. But I don't change into animals and I don't live forever. Not by a longshot. I'll be lucky to see thirty. So will my friends. We share the challenges of our disease, and the dream of living a normal life, as unlikely as that may be.
Fragment Based Drug Design
There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in...
