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This book is an extremely detailed account of all aspects of macromolecular mechanochemistry and will be of great interest to all experts in this area of rapidly advancing mechanochemistry. Mechanochemical transformations are the subject of increasing attention in solid state chemistry, physics and materials science as well as in development of advanced technologies. They have been discussed at a number of symposia on mechanochemistry and mechanical alloying in various countries. The book is divided into the following sections: Polystage feature of mechanochemical process Polymer mechanochemistry deformation Mechanodegradation Influence of some factors on mechanochemical degradation Effect of mechanodegradation on the structure and properties of polymers Polymer fracture Fracture of composite materials
Polymer Stress Reactions, Volume 2: Experiments provides an overall world perspective for the field of polymer reactions caused by stress. For the reader's benefit the book is developed along several lines for ease of reference. The same studies may thus be discussed from different points of view such as type of equipment, polymer used, basic parameters, and the polymer state. Presentation by polymer state is a fundamental, i.e., a molecular approach to mechanochemistry. The discussion of each nominal polymer state includes a description of those parameters and variables which are germane to the mechanically induced reactions in that state. In contrast, the variables which are generally applicable to mechanochemistry, such as temperature and shear intensity, are subsequently treated individually. The present volume contains two main chapters. The first reviews the principal experiments on each of the most researched polymers, both natural and synthetic; the second discusses studies of the polymer state in mechanochemistry.
The number-one reference on the topic now contains a wealth of new data: The entire relevant literature over the past six years has been painstakingly surveyed, resulting in hundreds of new descriptors being added to the list, and some 3,000 new references in the bibliography section. Volume 1 contains an alphabetical listing of more than 3300 descriptors and related terms for chemoinformatic analysis of chemical compound properties, while the second volume lists over 6,000 references selected from 450 journals. To make the data even more accessible, the introductory section has been completely re-written and now contains several "walk-through" reading lists of selected keywords for novice users.
Polyphenols Understand polyphenols and their benefits with this comprehensive overview Polyphenols are a group of beneficial compounds—including phenolic acids, flavonoids, anthocyanins, and others—that can be found in a vast range of plants and plant-based foods. Their health benefits and the variety of their applications in functional foods, dietary supplements, and similar areas have made polyphenols a $1 billion market, a figure that is expected to more than double in the next decade. This has placed increased emphasis on areas of cutting-edge research such as the use of bio-based nanodelivery systems to improve the oral bioavailability of polyphenols. Polyphenols constitutes a compr...
Significant progress has been made in the study of three-dimensional quantitative structure-activity relationships (3D QSAR) since the first publication by Richard Cramer in 1988 and the first volume in the series. 3D QSAR in Drug Design. Theory, Methods and Applications, published in 1993. The aim of that early book was to contribute to the understanding and the further application of CoMFA and related approaches and to facilitate the appropriate use of these methods. Since then, hundreds of papers have appeared using the quickly developing techniques of both 3D QSAR and computational sciences to study a broad variety of biological problems. Again the editor(s) felt that the time had come t...
Proceedings containing 231 manuscripts that were submitted and approved for the 13th biennial worldwide refractories congress recognized as the Unified International Technical Conference on Refractories(UNITECR), held September 10-13, 2013.
Bioethics is the application of ethics to the broad field of medicine, including the ethics of patient care, research, and public health. In this book, prominent authors from around the globe discuss the complexities of bioethics as they apply to our current world. Topics range from the philosophical bioethics of the evolution of thinking about marriage from a religious standpoint to the bioethics of radiation protection to value-based medicine and cancer screening for breast cancer. Bioethics in Medicine and Society is wide-ranging, with additional chapters on the ethics of geoengineering, complementary and alternative medicine, and end-of-life ethical dilemmas. Readers with find that the field of bioethics has broad implications throughout society from our most intimate interpersonal relationships to policies being implemented on a global scale.
Studies in Natural Products Chemistry, Volume 78 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores
In recent years there have been significant advances in the knowledge of risk factors, gene-environment interactions, incidence, prevalence, outcomes, and prevention strategies of many neurological disorders. These advances have been accompanied by developments in study design methodologies and statistical analysis. This handbook bridges the gap between current neuroepidemiological knowledge and its evidence-based application in everyday practice.
This book exclusively focuses on the science and fundamentals of polymer gels, as well as the numerous advantages that polymer gel-based materials offer. It presents a comprehensive collection of chapters on the recent advances and developments in the core science and fundamentals of both synthetic and natural polymer-based gels, and pays particular attention to applications in the various research fields of biomedicine and engineering. Key topics addressed include: polysaccharide-based gels and their fundamentals; stimuli-responsive polymer gels; polymer gels applied to enzyme and cell immobilization; chitosan-based gels for cancer therapy; natural polymeric and gelling agents; radiation dosimetry; polymeric gels as vehicles for enhanced drug delivery across the skin; transport in and through gel; and polymer gel nanocomposites and functional gels. The book’s extensive and highly topical coverage will appeal to researchers working in a broad range of fields in industry and academia alike.