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This issue of Endocrinology and Metabolism Clinics, edited by Dr. Robert Rapaport, is devoted to Pediatric Endocrinology. Articles in this issue include: Thyroid Cancer in Pediatrics; Gender and Sex Assignment; CAH Prenatal Diagnosis; Diabetes; Polycystic Ovarian Disease; Newborn Screening for X-linked ALD; Growth in Patients w/ Skeletal Dysplasia; Thyroid Imaging in Infants; Bariatric Surgery in Youth; Pituitary Imaging in Pediatrics; and Cardiac and Metabolic Features of GH Deficiency.
The last thing Andi needs is a cocky FBI agent... Badboy FBI agent Cole Lucas always gets his man. So when the unthinkable happens and one gets away, Cole grits his teeth and hunts the human trafficker all the way to Antioch, Texas, where he collides with Detective Andi MacLaren. Cole doesn’t do small towns and he doesn’t get involved with women he works with, but Andi tempts him in ways he doesn’t want to acknowledge. Two murders, her partner shot and leading the investigation on her own, the last thing Andi needs is a cocky FBI agent that sees her as no more than a tagalong. As a widow and single mother, she’s used to being on her own. When Cole gets stuck without a place to stay, crashing on her couch puts them in dangerous territory. Attraction and passion bring Andi to a place she left behind when her husband died. Her three-year-old son quickly wiggles his way into Cole’s heart, and he starts contemplating things—family, love—that he’d never planned for himself. Can being forced to work together make them stronger or will their differences jeopardize their case and their hearts?
Many factors may influence the release of neurotransmitters from airway nerves [1]. This is likely to be important in physiological control of airway functions and may be particularly relevant in airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD). Neural elements in airways interact in a complex manner and the activation of certain neural pathways may profoundly influence the release of transmitters from other neural pathways. Similarly inflamma tory mediators released from inflammatory cells in the airways may also modulate neurotransmitter release. There are marked differences be tween species in airway innervation and in neuromodulatory effects and, wherever ...
Glycobiology involves studies of complex carbohydrates and posttrans- tional modifications of proteins, and has become an important interdiscip- nary field encompassing chemistry, biochemistry, biology, physiology, and pathology. Although initial research was directed toward elucidation of the different carbohydrate structures and the enzymes synthesizing them, the field has now moved toward identifying the functions of carbohydrates. The pro- cols described in Glycobiology Protocols form a solid basis for investigations of glycan functions in health and disease. The cloning of many of the genes participating in glycosylation processes has helped to enhance our knowledge of how glycosylation...
This practical resource provides the latest evidence, management strategies and recommendations for the treatment of disorders of the adrenal glands, including related physiology, genetics and pharmacology. This book is divided into three thematic sections. The first covers adrenal physiology, presenting adrenal zonation and development, the regulation of steroidogenesis, and the pharmacology of glucocortisoids. Part two discusses the genetics and pathophysiology of a number of adrenal disorders, including autoimmune Addison’s disease, congenital adrenal hyperplasia, primary aldosteronism, adrenocortical tumors and hyperplasias, and pheochromocytomas and paragangliomas. The final section p...