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Diagnostics and Gene Therapy for Human Genetic Disorders provides an integrative and comprehensive source of information blending classical human genetics with the human genome. It provides a multidisciplinary overview of Mendelian inheritance and multifactorial inheritance, genetic variations, polymorphisms, chromosomal, multifactorial, and mitochondrial disorders. PCR, electrophoresis, cytogenetics, prenatal, and HPLC based techniques applied for diagnosing genetic disorders are discussed with applications. Symptoms, etiology, diagnosis, treatment of 14 major and 5 minor genetic disorders are discussed in detail. Methods employed for the preparation of kits for the diagnosis of diseases ar...
This book is a research publication that covers original research on developments within the Design of Experiments - Applications field of study. The book is a collection of reviewed scholarly contributions written by different authors and edited by Dr. Messias Borges Silva. Each scholarly contribution represents a chapter and each chapter is complete in itself but related to the major topics and objectives. The target audience comprises scholars and specialists in the field.
This volume reviews the drinking water treatments in which AOPs display a high application potential. Firstly it reveals the typical supply sources and limitations of conventional technologies and critically reviews natural organic matter characterization and removal techniques, focusing mainly on AOP treatments. It then explores using AOPs for simultaneous inactivation/disinfection of several types of microorganisms, including highly resistant Cryptosporidium protozoa. Lastly, it discusses relevant miscellaneous topics, like the most promising AOP solid catalysts, the regime change of Fenton-like processes toward continuous reactors, the application of chemometrics for process optimization,...
Num período marcado por profundas transformações a nível social e económico resultantes da crise que afetou a economia europeia desde finais da década de 2000, Portugal tem registado significativas alterações no quadro de relações laborais, na disponibilidade do emprego, nos valores salariais praticados e nos níveis de proteção social que disponibiliza aos cidadãos. Os trabalhadores imigrantes, frequentemente inseridos no “mercado de trabalho secundário”, foram duramente afetados por estas transformações estruturais, apresentando sistematicamente taxas de desemprego mais elevadas do que os nacionais e níveis remuneratórios mais baixos. A sua enorme dependência dos ren...
The Atlantic Forest is one of the 36 hotspots for biodiversity conservation worldwide. It is a unique, large biome (more than 3000 km in latitude; 2500 in longitude), marked by high biodiversity, high degree of endemic species and, at the same time, extremely threatened. Approximately 70% of the Brazilian population lives in the area of this biome, which makes the conflict between biodiversity conservation and the sustainability of the human population a relevant issue. This book aims to cover: 1) the historical characterization and geographic variation of the biome; 2) the distribution of the diversity of some relevant taxa; 3) the main threats to biodiversity, and 4) possible opportunities to ensure the biodiversity conservation, and the economic and social sustainability. Also, it is hoped that this book can be useful for those involved in the development of public policies aimed at the conservation of this important global biome.
Villa-Lobos and Modernism: The Apotheosis of Cannibal Music provides a new assessment of the Brazilian composer Heitor Villa-Lobos in terms of his contributions to the Modernist Movement of the twentieth century. In this profound study, Ricardo Averbach elevates Cultural Cannibalism as a major manifestation of the Modernist aesthetics and Villa-Lobos as its top exponent in the music field. Villa-Lobos’s anthropophagic appetite for multiple opposing aesthetics enlightens through the juxtaposition of contradictory elements, leaving a legacy of unmatched originality, a glittering kaleidoscope of sounds that draw from the radical power of Josephine Baker to the outrageous extravagance of Carme...
Dieses Buch führt ein in die Politik, die Ökonomie und die Gesellschaft Brasiliens, in seine zentralen politischen Institutionen, Akteure und Politikfelder. Es fragt insbesondere nach der Entwicklung der demokratischen Institutionen seit dem Ende der Militärdiktatur 1985 und der Rückkehr zur Demokratie und liefert zudem in jedem Kapitel eine erste Bilanz der in vielerlei Hinsicht bedeutsamen Regierung von Lula da Silva.
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