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Population-based cancer registries are an essential information source for quantifying the impact of cancer in a population and its evolution, planning and evaluation of cancer control policies and healthcare systems. In the last decades, the information provided by cancer registries has improved dramatically in quality and quantity. Technological advances and record linkage have contributed to data improvement. Therefore, clinical data collected by cancer registries such as stage, treatment, co-morbidity, etc. contribute to treatment effectiveness assessment and identification of inequality in health care access at the population level. The reliability and utility of the information provided by cancer registries depend on the quality of the data collected. On the other hand, cancer registries' data harmonisation is crucial for data use and comparability.
This book discusses the application of bioinformatics in cancer disease management. It covers general aspects of cancer as a disease but also as a success story in the translation of omics data in clinical settings. It provides an overview of the specific applications of bioinformatics tools in cancer epidemiology, prevention, and screening and in the identification of novel genetic and molecular biomarkers involved in cancer development. This is accomplished through the inclusion of numerous examples of the use of bioinformatics in precision oncology.
Diet quality is a broad term that encapsulates both perceived and actual practices, personal preferences and cultural diversity. Measuring dietary quality can be problematic and includes investigating food types, the number or size of portions or their frequency. Diet quality may also be related to the type of food being ingested, snacking and other eating habits. Manufactured beverages and fast food may also be included as well as microbiological quality and attempts to improve single food items such as meats or vegetables. In this book, Diet Quality: An Evidence-Based Approach, Volume 1 all of the major facets of diet quality in relation to health outcomes are covered. This important new t...
About 1,450 cases of childhood cancer are diagnosed each year throughout Great Britain. This book gives detailed information in tables and graphs on incidence, survival and mortality rates for the country, including trends since the 1960s.
A wide range of projects are described in the latest Biennial Report of the International Agency for Research on Cancer (IARC), the cancer research branch of the World Health Organization. Most of these projects involve collaborations with scientists in institutes throughout the world, covering topics ranging from descriptive epidemiology and biostatistics, cancer registration and analysis of data on cancer occurrence, to basic research on genetic and molecular aspects of cancer development to pathogenesis and prevention studies. Profusely illustrated, the Report also contains details of the personnel and organization of IARC and its activities, as well as a complete list of over 500 publications and articles authored by its scientists and their collaborators during the biennium.
The "Cancer Incidence in Five Continents" series presents data on cancer incidence in a standardized format for every area in the world from which it is possible to obtain reliable figures. Volume V, published in 1987, included data from population based cancer registries covering 137 populations in 36 countries. The publication depicts the data published in Volume V in a graphic format. This form of presentation allows a more easy appreciation of the range and pattern of incidence internationally, and highlights the interesting variations for the different cancer sites. Histograms of the world standardized rates illustrate the range in incidence for 40 geographically representative populations by cancer site and by sex, with the addition of bars showing the highest and lowest rates for each site among all the populations included in Volume V. Pie charts show the proportions of the top ten cancer sites within each of the 137 populations in Volume V. A series of graphs for 24 populations show the different pattern of incidence by age for 47 cancer sites.
The association between AIDS and cancer was recognized from the beginning of the AIDS epidemic, when the appearance of Kaposi sarcoma in a cluster of young men was one of the first signs of this new disease. It was soon recognized that AIDS was caused by infection with a novel virus (HIV) and that AIDS patients are prone to develop a number of “AIDS-defining” cancers: Kaposi sarcoma, lymphoma, and cervical cancer. The development of effective combination anti-HIV therapy starting around 1996 converted AIDS from a death sentence to a manageable disease and led to dramatic shifts in the epidemic. As this therapy was able to improve immune function in patients, the incidence of most “AIDS...
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This book is a compilation and discussion of data on the survival of cancer patients in 12 European countries. Measures of incidence, survival and mortality are critical to the interpretation of data on progress in the fight against cancer, and in the evaluation of the overall effectiveness of cancer control programmes. Randomized controlled clinical trials have shown many modern protocols for cancer treatment to be more effective than earlier treatments, but until now, comparable population-based survival figures have raraly been available. EUROCARE is a concerted action among European cancer registries, aimed at estimating and comparing the survival of cancer patients in different European...